Moxifloxacin 0.5% Eye prep

Moxifloxacin 0.5% Eye prep is an antibiotic, used in the treatment of bacterial infections of the eye. It relieves the symptoms of the infection by stopping the further growth of the causative microorganisms. Moxifloxacin 0.5% Eye prep is for external use only. Take it in the dose and duration as advised by your doctor. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. Avoid skipping any doses and finish the full course of treatment even if you feel better. It may cause eye discomfort, dry eyes and burning sensation in the eyes immediately following application. However, these side effects are temporary and usually subside on their own. Inform your doctor if they persist for a longer duration. It may cause short term blurring of vision when first used. Use caution before driving or using machines. Do not wear contact lenses while using it. Moxifloxacin 0.5% Eye prep is an antibiotic. It treats bacterial eye infections by preventing the bacteria from dividing and repairing. It does so stopping the action of a bacterial enzyme called DNA-gyrase.

Bacterial eye infections Bacterial conjunctivitis Moxifloxacin ophthalmic solution is indicated for bacterial conjunctivitis caused by susceptible strains of certain Gram-positive microorganisms, Gram-negative microorganisms, and Chlamydia trachomatis.

4-Quinolone preparations, Ophthalmic antibacterial drugs.

Fluoroquinolone / Quinolone antibacterial.

Moxifloxacin is an antibacterial agent that interferes with bacterial DNA replication, transcription, repair, and recombination.

Moxifloxacin inhibits the topoisomerase II (DNA gyrase) and topoisomerase IV required for bacterial DNA replication, transcription, repair and recombination.

Adult Dose: Ophthalmic Bacterial conjunctivitis Adult: As 0.5% soln: Instill 1 drop into the affected eye(s) bid-tid for 7 days. It can be used concomitantly with artificial tears, allowing a 15 minute interval between products. Child Dose: Ophthalmic Bacterial conjunctivitis Child: >1 yr: Instill 1 drop into the affected eye(s) tid for 7 days.

For ophthalmic use only. Check the label directions before use. Hold the dropper close to the eye without touching it. Instill the prescribed number of drops into the lower eyelid. Wipe away excess liquid. Do not allow the dropper tip to touch the eye or any surface. When using another ophthalmic medicine, allow an interval of about 5–10 minutes. When used with artificial tears, a 15-minute interval may be maintained between the products.

If you miss a dose of Moxifloxacin 0.5% Eye prep, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Eye discomfort • Dry eye • Burning sensation

Use only as directed by a registered physician. Do not touch the dropper tip to the eye or any surface. Contact lenses should not be worn when signs and symptoms of bacterial conjunctivitis are present. Temporary blurred vision may occur after application. Use caution when driving or operating machinery if vision is temporarily blurred. Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. Clinical examination, including slit-lamp biomicroscopy or fluorescein staining, may be required when clinically indicated. The source states that the preparation should not be used after one month of first opening.

Patients with a history of hypersensitivity to Moxifloxacin, to other Quinolones or to any of the components in this medication

Additive effect on QT interval prolongation w/ other drugs that prolong QT interval (e.g. erythromycin, TCAs, antipsychotic agents). Decreased absorption and bioavailability w/ Al- or Mg-containing antacids, or Fe or Zn preparations. Concomitant use of corticosteroids increases the risk of severe tendon disorders esp in elderly (>60 yr). Decreased absorption w/ sucralfate or didanosine. Potentially Fatal: Concurrent use of class Ia (e.g. quinidine, procainamide) or III (e.g. amiodarone, sotalol) antiarrhythmic drugs or w/ other drugs that prolong QT interval (e.g. erythromycin, TCAs, antipsychotic agents) may cause additive effect on QT interval prolongation.

No interaction found/established

[CONSULT YOUR DOCTOR] Moxifloxacin 0.5% Eye prep may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Moxifloxacin 0.5% Eye prep is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

According to the source, for bacterial conjunctivitis in children above 1 year of age, 1 drop into the affected eye(s) three times daily for 7 days is specified.

No specific geriatric dosage or separate administration instruction is provided in the source.

The source does not establish a specific interaction or adjustment for renal or hepatic impairment.

Specific information regarding overdose of ophthalmic Moxifloxacin is not provided in the source.

Store below 25°C. Do not freeze. Store in a cool and dry place. Protect from light. Keep out of reach of children. Do not allow the dropper tip to touch any surface. Do not use after one month of first opening.

The chemical structure or molecular formula of Moxifloxacin is not provided in the source.