Nimodipine

Nimodipine is a medicine used to treat and prevent further damage to the brain after bleeding around the brain (subarachnoid hemorrhage or SAH). It is known as a calcium channel blocker and helps to improve blood flow to the brain and prevent changes in brain function. Nimodipine is usually started as soon as possible after bleeding around the brain (or SAH) is confirmed by the doctor. The exact dose and frequency will be decided by your doctor depending on your medical condition and response to treatment. It may be taken empty stomach or with a meal, but take it regularly as per your doctor's instructions, to get the most benefit. Do not take any antacids for 2 hours before or after taking Nimodipine as this can prevent the medicine from working properly. Do not stop taking this medicine without first consulting your doctor. Your condition may worsen if this medicine is stopped too soon. The most common side effects include decreased blood pressure, increased heart rate (tachycardia), headache, stomach discomfort, nausea, rash, muscle cramp, and edema (swelling over the whole body). Consult your doctor If any of these bother you, or get worse, or do not go away. Before taking Nimodipine, let your doctor know if you have any heart or liver-related problems. Some other medicines may affect the way it works, especially some medicines used to treat seizures (fits) and those used to treat high blood pressure or heart conditions. Please tell your doctor about all the medicines you are taking to make sure you are safe. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. Your doctor will keep a watch on your blood pressure while you are taking this medicine. Nimodipine is a calcium channel blocker. It relaxes the narrow blood vessels in the brain and makes the blood flow more easily. This prevents brain damage after bleeding around the brain.

• Subarachnoid haemorrhage

Nimodipine inhibits inflow of Ca ions into cells by blocking Ca channels or select voltage-sensitive areas resulting in relaxation of vascular smooth muscle and myocardium during depolarisation. Nimodipine has greater action on the cerebral vessels because of its high lipophilicity.

Adult Dose: Oral Prophylaxis of neurological deficit following subarachnoid haemorrhage Adult: 60 mg 4 hrly beginning w/in 4 days of onset of haemorrhage and continued for 21 consecutive days. Hepatic impairment: Initially, 30 mg 4 hrly.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nimodipine may be taken with or without food, but it is better to take it at a fixed time.

Common: • Decreased blood pressure • Headache • Increased heart rate • Nausea • Rash • Stomach discomfort • Edema (swelling) • Muscle cramp

[UNSAFE] Nimodipine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Take it as per dose and duration suggested by your doctor. Do not take any antacids for 2 hours before or after taking Nimodipine as it may affect the working of the medicine. A sudden drop in your blood pressure may occur, especially when you first start taking Nimodipine. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Your doctor will monitor your blood pressure and heart rate during the treatment with this medicine. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding.

Use w/in 1 mth of MI or an episode of unstable angina. Concomitant use w/ potent CYP3A4 inhibitors (e.g. clarithromycin, ritonavir, ketoconazole, nefazodone).

Plasma concentration and efficacy may be significantly reduced when administered w/ strong CYP3A4 inducers (e.g. rifampicin, carbamazepine, phenobarbital, phenytoin). May increase serum levels and toxicity of phenytoin. Increased plasma concentrations w/ cimetidine or sodium valproate. Potentially Fatal: Increased risk of significant hypotension w/ concomitant potent CYP3A4 inhibitors (e.g. clarithromycin, ritonavir, ketoconazole, nefazodone).

[UNSAFE] Nimodipine may cause excessive drowsiness with alcohol.

[CONSULT YOUR DOCTOR] Nimodipine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Nimodipine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[SAFE IF PRESCRIBED] Nimodipine is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nimodipine may not be needed in these patients. Please consult your doctor. [CAUTION] Nimodipine should be used with caution in patients with severe liver disease. Dose adjustment of Nimodipine may be needed. Please consult your doctor.

He got brain haemorrhage. He has type2 diabetic Pl suggest daily diet chart. We are north Indian family What guidelines doctor has given My Mother is a brain haemorrhage Patient and doctor has advised RILUTEK 50MG OR RILUZOLE, I seek advice whether to take RILUTOR 50MG for my mother or not. not needed in my opinion patient Has Brain Haemorrhage, And Pneumonia Too And Having Bedsores Too Please Help Me Out What Should I Do Now Kindly consult to any good Ayuvedic Panchkarma center. Panchkarma therapy will give you some result . He had a brain haemorrhage 1 n a half month back. He has partial memory loss and irrelevant talks. Balance is weak. Plz suggest what should i do. Take medicine Add t strocit 1 g bd Repeated(3) haemorrhage in right eye within 3 years.BP under control, no sugar All the times laser treatment was done and now last month it again happened and my visibility in that eye is blurred and blood not settled, cataract is also developing. The images are of low quality cannot see anything I am 14 weeks pregnant and had bleeding from last 2 weeks I had my USG done twice in last 3 weeks and it is showing Baby is fine But it is mentioned that there is a small Haemorrhage(5.7 ml) seen at lower pole In my last USG it is mentioned that there is Haemorrhage(10 ml) seen which is reduced to 5ml in my 2nd USG but again showing 5.7 in my latest one. I have been admitted for a week in hospital and discharged after that but 2 days back i have seen some more bleeding with some lower abdominal pain with some clots in the bleeding after that which I have done my latest USG in which it shows baby is fine and 5.7 inch haemorrhage. I am worried now and scared that it might lead to some worst conditions Please suggest me if this can be controlled I have attached my discharge medications and USG reports. Please help me with the answer You need to take care of few things- avoid travelling, avoid intercourse and lifting heavy weights. The bleeding should reduce. The blood collection inside will get absorbed with time. If at any time you notice fresh bleeding then contact your My tablet now XL.Dibitick tablet s What u want to know