Generic
Pelargonium Sidoides
3 brands available in the market
At a glance
Pelargonium Sidoides is an herbal medicine used for symptoms of upper respiratory tract infections including common cold, cough, blocked or runny nose, sore throat, rhinosinusitis, tonsillopharyngitis, and acute and chronic bronchitis.
Description
A standardized extract of Pelargonium sidoides was registered in 2005 by the German Federal Institute for Drugs and Medical Devices for acute bronchitis. Several randomized, double-blind, placebo-controlled clinical trials support the efficacy and safety of Pelargonium sidoides for the treatment of acute bronchitis in adults and children. The European Medicines Agency (EMA) also recommends Pelargonium for the treatment of common cold symptoms.
Indications
- Common cold, cough, blocked or runny nose, sore throat
- Rhinosinusitis
- Tonsillopharyngitis
- Acute and chronic bronchitis
Therapeutic class
Herbal and Nutraceuticals
Pharmacological class
Herbal Antimicrobial & Immunomodulator
Pharmacology
Pelargonium sidoides extract shows growth inhibitory effect against several bacterial strains (Klebsiella pneumoniae, E. coli, Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus aureus). It completely suppresses replication of Influenza A virus (H1N1, H3N2), Respiratory Syncytial Virus (RSV), Rhinovirus, Coronavirus, Parainfluenza virus, and Coxsackie virus. It inhibits pathogen-host cell interaction, increases ciliary beat frequency, and boosts the immune system through macrophage activation.
Mechanism of action
Inhibits viral and bacterial pathogen growth, thins and loosens airway mucus, and stimulates the immune system through macrophage activation.
Dosage
Tablet Dosage:
- Adults & >12 years: 1 tablet 3 times daily
- 6-12 years: 1 tablet 2 times daily
Syrup Dosage:
- Adults & >12 years: 7.5 mL 3 times daily
- 6-11 years: 5 mL 3 times daily
- 1-5 years: 2.5 mL 3 times daily
Administration
- Follow the prescribed dosage
- Take at the same time each day
- Follow the duration as advised by your doctor
Missed dose
If you miss a dose, take it as soon as you remember; skip if it's almost time for next dose; do not double the dose.
Side effects
Side Effects:
- No side effects reported yet
- Rare cases: Excessive dose may cause stomach pain, heartburn, nausea, or diarrhea
Precautions & warnings
- Do not use in severe liver or kidney disease
- Follow the prescribed dosage
Contraindications
- Hypersensitivity to any of the ingredients
- Severe liver or kidney disease
Drug interactions
No known interactions.
Food interactions
Take with food for better absorption.
Use in pregnancy
Use in Pregnancy: Should not be taken during pregnancy.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Should not be taken during breastfeeding.
Pediatric use
Safety not established in children under 1 year.
Geriatric use
Caution required in elderly patients; consult your doctor.
Renal / hepatic impairment
Renal Impairment: Do not use in severe kidney disease.
Hepatic Impairment: Do not use in severe liver disease.
Overdose effects
No overdose information available; consult your doctor if taken in excess.
Storage conditions
Store below 30°C in a dry place, protected from light; keep out of reach of children.
Chemical structure
Pelargonium Sidoides