Piroxicam

Piroxicam is a pain relieving medicine. It is used to treat moderate to severe pain in condition such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles. Piroxicam should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it. The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine. Piroxicam is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).

• Pain relief

Piroxicam is a NSAID, belonging to the oxicam group. It inhibits prostaglandin synthesis, reduces fever by acting on the heat-regulating center of the hypothalamus, inhibits platelet-aggregating substance thromboxane A2 and reduces pain receptor sensitivity. It also exerts anti-inflammatory effect by lysosomal stabilisation, kinin and leukotriene production, alteration of chemotactic factors and neutrophil activation inhibition.

Adult Dose: Adult: Rheumatic disorders Initial: 20 mg/day as a single dose. Maintenance: 10-30 mg in single or divided doses. Acute gout 40 mg/day for 5-7 days. Acute musculoskeletal conditions; Post-op pain Initial: 40 mg/day for 2 days. Maintenance: 20 mg/day for 1-2 wk. Child Dose: Juvenile idiopathic arthritis Child: >6 yr: 46 kg: 20 mg. Doses to be taken once daily.

Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Piroxicam is to be taken with food.

If you miss a dose of Piroxicam, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Vomiting • Stomach pain • Nausea • Indigestion • Diarrhea

[UNSAFE] Piroxicam may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Dolonex DT 20mg Tablet helps relieve pain and swelling of various joints and muscles. Take it with food to avoid stomach upset. Your doctor will prescribe you the lowest effective dose of this medicine for the shortest possible time necessary to relieve your symptoms. It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you. Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.

Hypersensitivity or asthma-type reactions to piroxicam, aspirin or other NSAIDs. History or active GI ulceration, bleeding and perforation; history of GI disorders that predispose to bleeding disorders (e.g. ulcerative colitis, Crohn's disease, GI cancers or diverticulitis). Treatment of perioperative pain in the setting of CABG surgery. Concomitant use w/ aspirin, other NSAIDs and anticoagulants.

Increased risk of GI bleeding w/ anti-platelets and SSRIs. May exacerbate cardiac failure, reduce GFR and increase plasma glycoside levels. Increased risk of nephrotoxicity w/ ciclosporin and tacrolimus. Increased absorption w/ cimetidine. Increased risk of GI ulceration w/ corticosteroids. May interfere w/ the natriuretic action of diuretics. May displace other highly protein-bound drugs. May increase steady state plasma lithium levels. May antagonise the effect of antihypertensives. May reduce the excretion of methotrexate, leading to acute toxicity. Increased risk of convulsions w/ quinolones. May interfere w/ mifepristone-mediated termination of pregnancy. Potentially Fatal: May enhance the effect of anticoagulants (e.g. warfarin). Increased risk of serious GI events w/ aspirin and other NSAIDs.

[UNSAFE] It is unsafe to consume alcohol with Piroxicam.

[CONSULT YOUR DOCTOR] Piroxicam is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[SAFE IF PRESCRIBED] Piroxicam is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

[CAUTION] Piroxicam should be used with caution in patients with severe kidney disease. Dose adjustment of Piroxicam may be needed. Please consult your doctor. No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine. [CAUTION] Piroxicam should be used with caution in patients with liver disease. Dose adjustment of Piroxicam may be needed. Please consult your doctor.

My tooth heavily pains sometime. As I have cavity please suggest me a tablet for immediate pain killer. Use dolonex dt twice dailyAfter relieving pain get ur teeth root canal treated by a dentist Pain in the knees for last 1 year. Please suggest best possible medicines. please send me ur latest standing knee X-rays please avoid taking dolonex dt at ur age Sir, My grandmother are face very big problem in there leg,knee,hand and all over the body lot of pain. Please recommend any painkillers(without side effect). Take Tab Dolonex-DT twice dailyDo following investigations RA factor, ESR, CRP, S.uric acid i have severe tooth ache many times, what drug should i take for this, please tell me the name of drugs Start using tab dolonex dt teice daily for today ,consult a dentist after dis I am suffering with lower backache, muscular pain. Had it last month too and had dolonex for 3 days.My cholesterol is high, should I take dolonex again? You may take it for relief but cause of low back ache needs evaluation Get a vit D3/ vit B12/ MRI lumbo sacral spine And avoid bending forwards Joint pain in my right knee since last fifteen day kindly suggest me Apply Dynapar QPS spray and take Tab Dolonex-DT twice daily and Tab Flotrip-forte thrice daily and Cap Pansec-DSR once daily empty stomach for 5 days Sevior pain during monthly period. She has taken one dosage of Tab. DT DOLONEX about an hour back but still no releaf Inj voveran is given now Hi PATIENT to 1mgdoctors. Severe pain in periods can be very problematic and can be due to many causes. I suggest you atleast get an ultrasound scan of pelvis done to look for the cause. Also it would be good to get physically examined by a doctor for complete evaluation and treatment. Pain in joints (knee & back), suffered with chicken guniea 4 months back. Please suggest Apply Dynapar QPS spray and take Tab Dolonex-DT twice daily and Tab Flotrip-forte thrice daily and Cap Pansec-DSR once daily for 5 daysDrink plenty of water