Generic
Povidone Iodine 7.5% Scrub
4 brands available in the market
At a glance
Povidone Iodine 7.5% Scrub is an antiseptic and disinfectant used for preoperative and postoperative hand and skin cleansing. It kills harmful microbes and controls their growth.
Description
Povidone-iodine is an iodophore with powerful broad-spectrum germicidal activity against bacteria, viruses, fungi, protozoa, and spores. It oxidizes cell constituents and iodinates proteins, inactivating them. The 7.5% formulation is used as a surgical scrub.
Indications
- Preoperative and postoperative hand and skin cleansing
- Surgical personnel and patient skin preparation
Therapeutic class
Iodine compounds (Anti-septic Preparations)
Pharmacological class
Antiseptic Scrub (Povidone-Iodine)
Pharmacology
Povidone-iodine slowly releases elemental iodine, providing prolonged germicidal activity. The 7.5% scrub formulation is effective for preoperative hand and skin cleansing.
Mechanism of action
Prevents infection by killing harmful microorganisms.
Dosage
Adult Dose (Topical):
- Preoperative hand washing: Wet hands, pour 5 mL solution on palm, rub for 2 minutes to develop suds, rinse thoroughly under running water
- Pre- and post-operative skin cleansing: After skin is shaved and wet, apply scrub, rub for minimum 2 minutes, rinse with sterile gauze saturated with water
Administration
- Check the label before use
- Wet hands and apply 5 mL solution
- Rub for 2 minutes to develop suds
- Rinse thoroughly under running water
Missed dose
If you miss a dose, apply it as soon as you remember; skip if it's almost time for next application; do not double the dose.
Side effects
Side Effects:
- No common side effects seen
- Skin irritation (rare)
Precautions & warnings
- Avoid prolonged use in patients with thyroid disorders or on lithium therapy
- Caution when regular applications to broken skin are made to patients with pre-existing renal insufficiency
- Avoid concurrent use with lithium therapy
Contraindications
- Hypersensitivity to povidone iodine or any ingredient
- Prolonged use in thyroid disorders
- Lithium therapy
Drug interactions
- Concurrent use with lithium therapy may exhibit hypothyroid effect
Food interactions
Not food-related (topical use).
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy; animal studies have shown harmful effects; consult your doctor.
Use in lactation
Use in Lactation: Safe during breastfeeding; human studies show insignificant transfer to breast milk.
Pediatric use
Safety not established in children; consult your doctor.
Geriatric use
Caution required in elderly patients; consult your doctor.
Renal / hepatic impairment
Renal Impairment: Caution when regular applications to broken skin are made to patients with pre-existing renal insufficiency; consult your doctor.
Hepatic Impairment: Caution in liver disease; consult your doctor.
Overdose effects
No overdose information available; consult your doctor if overused.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.
Chemical structure
Povidone Iodine 7.5% Scrub