Generic
Prednisolone 1% Eye prep
16 brands available in the market
At a glance
Prednisolone 1% Eye Prep is used for the treatment of redness and swelling in the eyes caused by infection or allergy. It is a steroid that provides relief from redness, itchiness, and soreness by blocking the production of chemical messengers that cause inflammation.
Description
Prednisolone decreases inflammation by inhibiting migration of polymorphonuclear leukocytes and reversing increased capillary permeability. It suppresses the immune system by reducing the activity and production of lymphocytes and eosinophils.
Indications
- Redness and swelling in the eye (due to infection or allergy)
- Conjunctivitis
- Ocular inflammation
Therapeutic class
Ophthalmic Non-Steroid drugs
Pharmacological class
Ophthalmic Corticosteroid
Pharmacology
Prednisolone inhibits polymorphonuclear leukocyte migration and reverses increased capillary permeability, reducing inflammation. It suppresses the immune system by reducing lymphocyte and eosinophil activity and production.
Mechanism of action
Reduces ocular inflammation and allergy by blocking inflammatory mediator production.
Dosage
Adult Dose (Ophthalmic):
- Conjunctivitis/Ocular inflammation: Instill 1-2 drops into affected eye(s) 2-4 times daily
- Higher frequency may be used during initial 24-48 hours if needed
Administration
- Shake the bottle well before use
- Do not touch the dropper tip to any surface or eye (to prevent contamination)
- Remove contact lenses before application and reinsert after 15 minutes
- Apply pressure on the corner of the eye (near the nose) for 1 minute after instillation
Missed dose
If you miss a dose, apply it as soon as you remember; skip if it's almost time for next application; do not double the dose.
Side effects
Common Side Effects:
- Burning sensation in the eye
- Eye irritation
- Blurred vision (temporary)
- Watery eyes
Precautions & warnings
- May affect driving ability (blurred vision)
- Do not use for longer than prescribed (risk of glaucoma or secondary infection)
- Use within 4 weeks of opening
- Do not stop suddenly without consulting your doctor
Contraindications
- Epithelial defect
- Glaucoma
- Herpes, vaccinia, varicella, and other viral diseases of cornea or conjunctiva
- Mycobacterial infection of the eye
- Fungal diseases of ocular structures
- Hypersensitivity to any ingredients
Drug interactions
No known interactions.
Food interactions
Not food-related (topical use).
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy; animal studies have shown harmful effects; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Safe during breastfeeding; human studies show insignificant transfer to breast milk.
Pediatric use
Safety not established in children; consult your doctor.
Geriatric use
Caution required in elderly patients; consult your doctor.
Renal / hepatic impairment
No interactions found/established for kidney and liver disease.
Overdose effects
No overdose information available; consult your doctor if overused.
Storage conditions
Store in a cool and dry place; do not use longer than 4 weeks after opening; keep out of reach of children.
Chemical structure
Prednisolone 1% Eye Prep