Generic
Rabeprazole + Domperidone
1 brands available in the market
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| Brand | Company | Form | Price/unit |
|---|---|---|---|
| Rebozen-40 DSR40mg | Leeford Healthcare Ltd | Capsule | ৳ 22 |
At a glance
Rabeprazole + Domperidone — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Rabeprazole + Domperidone is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms of acidity such as heartburn, stomach pain, or irritation. It also neutralizes the acid and promotes easy passage of gas to reduce stomach discomfort. Rabeprazole + Domperidone is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effects are diarrhea, stomach pain, dryness in mouth, headache, flatulence, and weakness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results. Before you start taking this medicine it is important to inform your doctor if you are suffering from kidney or liver disease. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding. Rabeprazole + Domperidone is a combination of two medicines: Domperidone and Rabeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Rabeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Indications
• Gastroesophageal reflux disease (Acid reflux) • Peptic ulcer disease
Mechanism of action
Rabeprazole is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase at the secretory surface of the gastric parietal cell. Domperidone is a peripheral dopamine-receptor blocker. It increases oesophageal peristalsis, enhances gastroduodenal coordination and lowers oesophageal sphincter pressure, gastric motility and peristalsis, thus facilitating gastric emptying and decreasing small bowel transit time.
Dosage
Adult Dose: Adult & adolescent >12 yr 1 cap once daily for 4-8 wk.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rabeprazole + Domperidone is to be taken empty stomach.
Side effects
Common: • Diarrhea • Stomach pain • Dryness in mouth • Headache • Dizziness • Flatulence • Weakness • Flu-like symptoms
Precautions & warnings
[UNSAFE] Rabeprazole + Domperidone may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Veloz D Capsule SR for the treatment of acidity and heartburn. Take it one hour before the meal, preferably in the morning. It is a well-tolerated medicine and provides relief for a long time. Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away. Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention. Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
Contraindications
Hypersensitivity to substituted benzimidazoles. Prolactinoma, severe hepatic impairment, GI hemorrhage, mechanical obstruction or perforation.
Drug interactions
Monitor for increase in INR & prothrombin time when given w/ warfarin, cyclosporine, ketoconazole, ritonavir, erythromycin.
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Rabeprazole + Domperidone. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Rabeprazole + Domperidone may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Rabeprazole + Domperidone is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[CAUTION] Rabeprazole + Domperidone should be used with caution in patients with kidney disease. Dose adjustment of Rabeprazole + Domperidone may be needed. Please consult your doctor. [CAUTION] Rabeprazole + Domperidone should be used with caution in patients with liver disease. Dose adjustment of Rabeprazole + Domperidone may be needed. Please consult your doctor. Use of Rabeprazole + Domperidone is not recommended in patients with moderate and severe liver disease.
Common questions
acid reflux, gastric, sugar stimulate acid reflux. CBC,ESR,LIPID PROFILE,URINE RE/CS, KFT, LFT, VIT D & B estimation,TAKE RABEKIND DSR once a day empty stomach FOR 3 week Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed Having problem of acid reflux disease with throat infection and pain in right side of abdomen take avipattikar churan 1 spoon twice before meal, for throat infection do gargles with lyuke warm water and mixing tankan bhasma a littlein it,, My cough is not getting cured since 4-6 months. Tried some doctors, their medicines work for some time and the dry cough starts again. Though it happens occasionally, but i still cough It can be allergic cough or acid reflux disease. Can't give more opinion without seeing Suffering from acid reflux disease due to which pain in throat and right side of lower abdomen Dear sir for the time being you can take Robinia 30, 04 drops in half cup water and Nixocid tab 2 tab thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a homeopath so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly, Moderate Throat Pain in left side Moderate Ear pain. Acid reflux too often it may be due to acidity also you may have got some ulcer or infection in that region visit ent specialist near you for proper examination As soon as I go to sleep I start coughing and it stops after i drink water. it feels like as if something has stuck in the throat. it is happening for the past few days. Same happen if i do not drink water for some time. Please help me with the solution. It can be due to acid reflux. Take tab pan D morning and zintac bed time . Try this What is the reason and perfect treatment for acid reflux? Hello, Welcome to 1mg consulting, Myself Dr.Satyam, MBBS.For acid reflux , take TAB.PAN-D twice a day half hour before food for 2 weeks.SYR.DIGENE 2 spoons before bedtime for 2 weeks.Avoid spicy food & fasting.Hope this helps.Happy to help you. Have a nice day :-)