Generic
Ranibizumab
1 brands available in the market
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| Brand | Company | Form | Price/unit |
|---|---|---|---|
| Lucentis10mg/ml | Nevian Lifescience PLC | Injection | ৳ 100,000 |
At a glance
Ranibizumab — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Ranibizumab is used for the treatment of eye diseases which are caused by diabetes, macular degeneration, and macular swelling. It reduces the abnormal growth and leakage of blood vessels in the eye that can cause vision loss. Ranibizumab is administered directly into the eyeball by an eye specialist. You should not self administer this medicine at home. The common side effects include eye pain, redness, blurred or decreased vision and eye discharge. However, if you experience these side effects for a longer duration or any other symptoms which you think may be due to this medicine, please inform your doctor. It is not advised to drive after administration of this injection as it may cause blurring of vision. Ranibizumab is an anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the growth and leakage of abnormal blood vessels in the eye(s) that may cause vision loss.
Indications
• Diabetic eye disease • Wet age-related macular degeneration • Macular oedema due to retinal vein occlusion
Mechanism of action
Humanized monoclonal antibody to VEGF-A, inhibits VEGF-A-induced ocular neovascularization.
Dosage
Adult Dose: Intravitreal Neovascular (wet) age-related macular degeneration Adult: 0.5 mg (0.05 mL of 10 mg/mL) mthly into the affected eye as a single dose. Continue treatment until visual acuity is stable for 3 consecutive mth. Doses are given at intervals of at least 1 mth. Macular oedema secondary to retinal vein occlusion Adult: 0.5 mg mthly into the affected eye as a single dose for 6 months. Doses are given at intervals of at least 1 mth. Diabetic Macular Edema, Diabetic Retinopathy with DME 0.3 mg (0.05 mL of 6 mg/mL) administer by intravitreal injection once a month (approximately every 28 days).
Administration
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Missed dose
If you miss a dose of Ranibizumab, please consult your doctor.
Side effects
Common: • Conjunctival hemorrhage • Eye pain • Eye inflammation • Increased intraocular pressure
Precautions & warnings
[UNSAFE] Ranibizumab may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear. Ranibizumab is used for the treatment of eye diseases caused by diabetes, macular degeneration and macular swelling. It is administered directly into the eyeball by an eye specialist. It may cause temporary visual disturbances. Don't drive or do anything that requires mental focus until you know how Ranibizumab affects you. Inform your doctor if you experience increased eye pain and redness, blurred or decreased vision, or increased sensitivity to light.
Contraindications
Active or suspected ocular or periocular infection, active severe intraocular inflammation, signs of irreversible ischaemic visual function loss in patients w/ retinal vein occlusion.
Drug interactions
May enhance the adverse/toxic effect of belimumab. Serious intraocular inflammation may occur when used adjunctively w/ verteporfin photodynamic therapy (PDT).
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Ranibizumab. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Ranibizumab may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Ranibizumab is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Ranibizumab is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ranibizumab may not be needed in these patients. Please consult your doctor. [SAFE IF PRESCRIBED] Ranibizumab is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Ranibizumab may not be needed in these patients. Please consult your doctor.
Common questions
Macular degeneration in left eye Get Oct done. n visit macular oedema in the right eye Hi Kindly once ophthalmologist retina / macular degeneration of left eye What kind. Send pic of ur prescription Diabetic macular edema treatment Laser or antivegf injection My father has AMD - Age related Macular Degeneration in left eye. It is a retina disease. Hence he has lower visibility in left eye. Doctor suggested to take injection of Avastin in eye. This is an off label medicine. Please advise us it is really work or not. Any other treatment is better than this? Yes it is off labelBut its costlier 3 times1 injection is not always enoughHe might need more no . of injections Sir, is surgery necessary in the initial stages of macular degeneration or it can be cured with medicines What kind of surgery. Macular degeneration can't be cured.Share pic of your prescription Sufferings from BRVO. Dr. advice for injection in eye. Is any other option for treatment of BRVO instead of injection in eye. Eye injection (anti VEGF) is the standard of care in BRVO with macular edema. the pros and cons will be explained by the treating doctor How to cure macular Amyloidosis Dear PATIENT is a chronic skin disease. Avoid sun and rubbing. Apply plenty of moisturiser. Sometimes it indicate underlying disease