Tizanidine

Tizanidine is a muscle relaxer. It provides relief from the discomfort associated with acute, painful musculoskeletal conditions such as rigidity, tension, stiffness, and muscle spasms. Tizanidine can be taken with or without food. Generally, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as this will make the medicine less effective. Some common side effects of this medicine include dry mouth, sleepiness, diarrhea, tiredness, and dizziness. If any of these side effects do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. To make sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine. Tizanidine is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles.

• Muscle relaxation

Tizanidine, an alpha2-adrenergic agonist, is a centrally acting muscle relaxant structurally related to clonidine. It reduces spasticity by increasing presynaptic inhibition of motor neurons and has no direct effect on skeletal muscle, the neuromuscular junction or on monosynaptic spinal reflexes.

Adult Dose: Oral Muscle Spasticity Spasticity associated with multiple sclerosis and spinal cord injury Initial: 2 mg q6-8hr; no more than 3 doses q24hr Maintenance: Increase by 2 to 4 mg until satisfactory response is achieved with minimum 1-4 days between dose increments Not to exceed 36 mg/day Painful muscle spasm associated with musculoskeletal conditions Adult: 2-4 mg tid. Elderly: Not recommended. Hepatic impairment: Avoid or use with extreme caution. Child Dose: Child < 18 years: Not recommended Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation <25 Initially, 2 mg once daily, gradually increasing the dose before increasing the frequency of admin.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tizanidine may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Tizanidine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Dizziness • Sleepiness • Dryness in mouth • Upset stomach

[UNSAFE] Tizanidine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Tizanidine provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system. Tizanidine may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. Avoid consuming alcohol when taking Tizanidine as it may cause excessive drowsiness. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.

Severe hepatic dysfunction.

Potentiates hypotensive effect of antihypertensives. Increased CNS effects with alcohol and CNS depressants. Increased bradycardia with ?-blockers and digoxin. Increased serum concentration of tizanidine with CYP1A2 inhibitors e.g. zileuton, ciprofloxacin and other fluoroquinolones, antiarrhythmics, cimetidine, famotidine, oral contraceptives, aciclovir and ticlopidine. Decreased serum concentrations of tizanidine with rifampicin. Use with caution with drugs that may prolong QT interval.

[UNSAFE] Tizanidine may cause excessive drowsiness with alcohol.

[CONSULT YOUR DOCTOR] Tizanidine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Tizanidine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CAUTION] Tizanidine should be used with caution in patients with kidney disease. Dose adjustment of Tizanidine may be needed. Please consult your doctor. [CAUTION] Tizanidine should be used with caution in patients with liver disease. Dose adjustment of Tizanidine may be needed. Please consult your doctor. Use of Tizanidine is not advised in patients with severe liver disease. Liver function tests are recommended before the start of treatment and then on a regular basis as advised.

Growth of extra muscle in nose Kanchnaar guggul 2 tab twice with water, vridhivadhika vati 2 tablet twice with water What is the treatment for muscle strength apart from exercise. Have muscle stiffness on neck and lower back. MRI shows nothing much and doctor suggest muscle weakness. Need to know longterm treatment which would be useful for getting muscle strength. https://www.1mg.com/otc/asthiposhak-tablet-otc325984One ?one tablet morning & evening after taking food , use at least 1-2 months Road accident. Now cured. Is physiotherapy mandatory after removal of POP?? Sir, I met with road accident exactly 63 days ago. Now POP is removed. Still can&#x27;t walk without walking aid. Doctor told physiotherapy is not required. And not suggested any exercises also for muscle relaxation. Sir, please suggest me , whether I should consult another doctor or exercises not always mandatory Physiotherapy is not mandatory Home exercises are needed for all cases My husband is having illicit relationship bcoz of that lot of problems. I am very tensed all the time. Please suggest a medicine to calm down. Thank you We understand your concernWe are here to helpYou are advised to solve problemAs medicine will help you for temporary periodDiscussing with husband and finding solution will calm you downTill then you can do Jacobson Progressive Muscle Relaxation""http://www.healthline.com/health/what-is-jacobson-relaxation-technique#wholebody-technique3Follow this link to find detailed procedure Hi sir, For the last 10 days I&#x27;m feeling excess of body heat and feeling like exhausted and tired. Some times muscle pains. So I&#x27;m taking FourtsB tablet which is a vitamin and mineral supplement i think. Though it gives mild relaxation, I&#x27;m not able to recover completely. Please suggest some medicine. Thanks. Take rich health nutra 1 Tablet daily of Charak company Have regular low back stiffness for which taking gabapin and Tizan 2mg. Doctor says I have a disc related problem in lower back.Have been taking medicine for 4 years and doctor says to go for surgery which I am avoiding. Please suggest some good medicine which can reverse my problem and hep me live a normal life. Rhus Tox 200 once a day in the morning for 3 months should help