Generic
Triamcinolone Acetonide
11 brands available in the market
At a glance
Triamcinolone Acetonide is a steroid used for allergic disorders, severe allergic reactions, and rheumatic disorders. It provides relief by preventing the release of substances that cause inflammation and by suppressing the immune system.
Description
Triamcinolone has mainly glucocorticoid activity. It suppresses the migration of polymorphonuclear leukocytes and reduces capillary permeability, thereby decreasing inflammation.
Indications
- Allergic disorders
- Severe allergic reactions
- Rheumatic disorder
Therapeutic class
Corticosteroid, Glucocorticoids
Pharmacological class
Corticosteroid
Pharmacology
Triamcinolone has mainly glucocorticoid activity. It suppresses the migration of polymorphonuclear leukocytes and reduces capillary permeability, thereby decreasing inflammation.
Mechanism of action
Blocks production of chemical messengers that cause inflammation and allergies, and suppresses the immune system.
Dosage
Adult Dose:
- IM: 20-80 mg deep IM into gluteal muscles
- Hay fever: 40-100 mg IM
- Rheumatic/arthritic disorders: 60 mg IM every 6 weeks
- Intra-articular: small joints 2.5-5 mg, larger joints 5-15 mg
- Intradermal: 1-3 mg/site
Child Dose: 6-12 years: 0.03-0.2 mg/kg IM every 1-7 days; >12 years: 60 mg IM every 6 weeks
Administration
- Administered by a doctor or nurse; do not self-administer
- Regular use at the right times increases effectiveness
- Do not stop until your doctor says it is safe
Missed dose
If you miss a dose, consult your doctor.
Side effects
Common Side Effects:
- Headache
- Infection
- Joint pain
- Injection site reaction
Precautions & warnings
- Does not usually affect ability to drive
- Mood changes or stomach problems may occur; inform your doctor
- Do not stop suddenly; may worsen symptoms
- Stay away from people with viral infections
- Regular medical tests may be needed for long-term use
Contraindications
- Sensitivity to active or inactive ingredients
- Untreated systemic fungal, bacterial, viral or parasitic infection
- Neonates (Parenteral)
Drug interactions
- Lowering of plasma salicylates levels
- NSAIDs: increased risk of GI bleeding and ulceration
- Antidiabetics: antagonised blood glucose-lowering effects
- Amphotericin B, beta agonists, beta-blockers, potassium-depleting diuretics, theophylline: increased risk of hyperkalaemia
- Ciclosporin, carbamazepine, phenytoin, barbiturate, rifampicin: increased clearance of triamcinolone
- Live vaccines: infections may develop
Food interactions
It is not known whether it is safe to consume alcohol with Triamcinolone Acetonide; consult your doctor.
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Caution needed; breastfeeding should be held until treatment is completed and drug is eliminated.
Pediatric use
Not recommended for premature infants and low birth weight infants (contains benzyl alcohol)
Geriatric use
Caution required in elderly patients
Renal / hepatic impairment
Renal Impairment: Limited information; consult your doctor
Hepatic Impairment: Limited information; consult your doctor
Overdose effects
Symptoms: Inflammation, hypertension, electrolyte imbalance.
Treatment: Supportive care.
Storage conditions
Store below 25°C, away from light and moisture; keep out of reach of children.