Generic
Trimebutine Maleate
3 brands available in the market
At a glance
Trimebutine Maleate — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Trimebutine Maleate is used in the treatment of pain due to smooth muscle spasm. It stops sudden muscle contractions (spasms), thereby relieving cramps, pain, and discomfort. Trimebutine Maleate is taken with or without in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effects are dryness in mouth, excessive thirst, reduced bronchial secretions, increased heart rate, flushing (sense of warmth in the face, ears, neck, and trunk), and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Before taking this medicine, you should let your doctor know if you have liver and kidney problems. .
Indications
• Pain due to smooth muscle spasm
Mechanism of action
Trimebutine is a GI motility regulator with antispasmodic properties.
Dosage
Adult Dose: Oral Irritable bowel syndrome Adult: 300-600 mg/day in 3 divided doses. Chronic gastritis Adult: 300 mg/day in 3 divided doses. Elderly: Use with caution.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trimebutine Maleate may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Palpitations • Increased heart rate • Arrhythmia (irregular heartbeats) • Excessive thirst • Reduce bronchial secretion • Dryness in mouth • Photophobia • Dry skin • Slow heart rate • Loss of accommodation • Flushing (sense of warmth in the face, ears, neck and trunk) • Dilatation of pupil • Difficulty in urination • Constipation
Precautions & warnings
[CONSULT YOUR DOCTOR] It is not known whether Trimebutine Maleate alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Do not drive or use machinery while using trimebutine as it may cause dizziness. Do not take alcohol as it may worsen the side effects of trimebutine. Avoid concomitant use of trimebutine with other medicine such as tubocurarine. Trimebutine is not recommended in children or adolescents under 12 years of age. Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Contraindications
Patients with known hypersensitivity to trimebutine maleate or any excipient.
Food interactions
[UNSAFE] Trimebutine Maleate may cause excessive drowsiness with alcohol.
Use in pregnancy
[CONSULT YOUR DOCTOR] Trimebutine Maleate may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Information regarding the use of Trimebutine Maleate during breastfeeding is not available. Please consult your doctor.
Renal / hepatic impairment
[CONSULT YOUR DOCTOR] There is limited information available on the use of Trimebutine Maleate in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Trimebutine Maleate in patients with liver disease. Please consult your doctor.