Generic
Urea Topical
11 brands available in the market
At a glance
Urea Topical is indicated for hyperkeratotic conditions such as dry rough skin, xerosis, ichthyosis, skin cracks and fissures, dermatitis, eczema, psoriasis, keratoses, and calluses.
Description
Applied topically, urea promotes hydration of keratin and mild keratolysis in dry skin. It increases water uptake by the stratum corneum and has an antipruritic effect.
Indications
- Dry rough skin
- Xerosis
- Ichthyosis
- Skin cracks and fissures
- Dermatitis
- Eczema
- Psoriasis
- Keratoses
- Calluses
Therapeutic class
Topical Keratolytic Agent
Pharmacological class
Topical Keratolytic
Pharmacology
Applied topically, urea promotes hydration of keratin and mild keratolysis in dry skin. It increases water uptake by the stratum corneum and has an antipruritic effect.
Mechanism of action
Promotes hydration of keratin and mild keratolysis in dry skin.
Dosage
Adult Dose (Topical):
- Ichthyosis and hyperkeratotic skin disorders: Apply 10-25% cream/lotion topically to affected skin twice daily
Administration
- Wash affected areas well
- Rinse off all traces of soap
- Dry and apply sparingly
- Avoid application to moist or broken skin and near the eye
Missed dose
If you miss a dose, apply it as soon as you remember; if almost time for next dose, skip it; do not double the dose.
Side effects
Common Side Effects:
- May produce local irritations (including erythema, burning or pruritus) and oedema when applied to sensitive, moist or fissured skin
Precautions & warnings
- Avoid application to moist or broken skin and near the eye
- Use with caution on sensitive skin
Contraindications
- Hypersensitivity to any of its components
Drug interactions
- Increased excretion of lithium
Food interactions
Food interactions are not significant.
Use in pregnancy
Use in Pregnancy: Consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Consult your doctor.
Pediatric use
Safety and efficacy not established in children
Geriatric use
Safe for elderly
Renal / hepatic impairment
Renal Impairment: Not applicable (topical application)
Hepatic Impairment: Not applicable (topical application)
Overdose effects
Overdose is not applicable (topical application).
Storage conditions
Store in a cool and dry place; keep out of reach of children.