Generic
Vitamin B complex + Vitamin C
3 brands available in the market
At a glance
This combination capsule is indicated in the treatment of patients with deficiencies of, or increased requirement for, vitamin B-complex and vitamin C.
Description
Vitamin B-Complex and Vitamin C function as cofactors of various enzymes which regulate carbohydrate, protein and fat metabolism.
Indications
- Deficiencies of, or increased requirement for, vitamin B-complex and vitamin C
- Decreased intake because of restricted or unbalanced diet (anorexia, diabetes mellitus, obesity, alcoholism)
- Reduced availability during treatment with antimicrobials
- Increased requirements due to increased metabolic rate (fever, acute or chronic infections, surgery, burns, fractures)
- Stomatitis, glossitis, cheilosis, paraesthesias, neuralgia, dermatitis
- Micronutrient deficiencies during pregnancy or lactation
Therapeutic class
Specific combined vitamin preparations
Pharmacological class
Vitamins & Minerals
Pharmacology
Vitamin B-Complex and Vitamin C function as cofactors of various enzymes which regulate carbohydrate, protein and fat metabolism. Thiamine (B1) acts as a cofactor in the decarboxylation of keto acids such as pyruvic acid. Riboflavin (B2) plays a vital role in cellular respiratory reactions in conjunction with nicotinamide.
Mechanism of action
B-complex vitamins and vitamin C support carbohydrate, protein, and fat metabolism and normal tissue function.
Dosage
Adult Dose (Oral):
- One capsule daily or as advised by the physician
Adult Dose (Injection):
- One vial (10 ml) daily
Child Dose (11 years and above) (Oral):
- 1-2 capsules daily
Child Dose (11 years and above) (Injection):
- One vial (10 ml) daily
Children below 11 years of age:
- Children weighing less than 10 kg should be given 1 ml of the dissolved mixture per kg body weight/day
- Children weighing 10 kg or more should be given 10 ml (one vial) of the dissolved mixture/day
Administration
- Take as directed by a physician
- Swallow tablets/capsules whole
Missed dose
If you miss a dose, take it as soon as you remember; if almost time for next dose, skip it; do not double the dose.
Side effects
Common Side Effects:
- The unwanted effects of nutrient solutions are a rise in the body temperature, shivering, chills and nausea and vomiting
- Allergic reactions (including anaphylaxis)
- Dermatological reactions (flushing, erythema, pruritus)
- CNS reactions (headache, dizziness, agitation)
Precautions & warnings
- Folic acid may mask the symptoms of pernicious anemia
- In patients receiving TPN, routine supplementation with both fat-soluble and water-soluble vitamins is recommended
- Daily vitamin requirements must be calculated to avoid over dosage and toxic effects, especially with regards to vitamins A & D and particularly in pediatric patients
- In patients for whom TPN is continued for prolonged periods, periodic monitoring of blood vitamin levels should be considered
- To prevent excessive excretion of water-soluble vitamins, daily dosage should be administered over a number of hours
Contraindications
- Hypersensitivity to any of the ingredients of the preparation
Drug interactions
- Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine
- Reduced serum concentrations with oral contraceptives
- Reduced effects in anaemia with parenteral chloramphenicol
Food interactions
Food interactions are not significant.
Use in pregnancy
Use in Pregnancy: Consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Consult your doctor.
Pediatric use
Pediatric dosage regimen established (11 years and above: 1-2 capsules daily; below 11 years: dosage by weight)
Geriatric use
Safe for elderly
Renal / hepatic impairment
Renal Impairment: Limited information
Hepatic Impairment: Limited information
Overdose effects
Symptoms: Hypervitaminosis.
Treatment: Supportive care.
Storage conditions
Store in a cool and dry place, away from light and children.