Generic
Vitamin B6, B9 & B12
2 brands available in the market
At a glance
These tablets are indicated for the distinct nutritional requirements of individuals under a physician's treatment for hyperhomocysteinemia; nutrient malabsorption or inadequate dietary intake; with particular emphasis for individuals with or at risk for atherosclerotic vascular disease in the coronary, peripheral, or cerebral vessels, or neurological disorders.
Description
Pyrodoxine (Vitamin B6) is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. Folic acid (Vitamin B9) is essential for the production of certain coenzymes in many metabolic systems. Cyanocobalamin (Vitamin B12) is vital to growth, hematopoiesis and nucleoprotein and myelin synthesis.
Indications
- Hyperhomocysteinemia
- Nutrient malabsorption or inadequate dietary intake
- Atherosclerotic vascular disease (coronary, peripheral, or cerebral vessels)
- Neurological disorders
Therapeutic class
Specific combined vitamin preparations
Pharmacological class
Vitamins & Minerals
Pharmacology
Pyrodoxine (Vitamin B6) is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. Folic acid (Vitamin B9) is essential for the production of certain coenzymes in many metabolic systems. Cyanocobalamin (Vitamin B12) is vital to growth, hematopoiesis and nucleoprotein and myelin synthesis.
Mechanism of action
Vitamins B6, B9, and B12 support normal metabolic function, hematopoiesis, and normal nervous system function.
Dosage
Adult Dose (Oral):
- Usual adult dose is one to two tablets daily or as directed by a physician
Administration
- Take as directed by a physician
- Swallow tablets whole
Missed dose
If you miss a dose, take it as soon as you remember; if almost time for next dose, skip it; do not double the dose.
Side effects
Common Side Effects:
- Allergic sensitization has been reported following both oral and parenteral administration of folic acid
- Paresthesia, somnolence, nausea and headache have been reported with pyridoxine hydrochloride
- Mild transient diarrhea, polycythemia vera, itching, transitory exanthema, and the feeling of swelling of the entire body has been associated with cyanocobalamin
Precautions & warnings
- Folic acid when administered as a single agent in doses above 0.1 mg daily may obscure pernicious anemia
- Unmetabolized Folic Acid has the potential to reduce natural killer cells cytotoxicity, which may result in an impaired immune response
Contraindications
- Known hypersensitivity to any of the components in the product
Drug interactions
- Pyridoxine Hydrochloride should not be given to patients receiving the drug levodopa, because the action of levodopa is antagonized by Pyridoxine Hydrochloride; however, Pyridoxine Hydrochloride may be used concurrently in patients receiving a preparation containing both carbidopa and levodopa
- Concurrent use of phenytoin and folic acid may result in decreased phenytoin effectiveness
Food interactions
Food interactions are not significant.
Use in pregnancy
Use in Pregnancy: Pregnancy category- Not classified.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Consult your doctor.
Pediatric use
Safety and efficacy not established in children
Geriatric use
Safe for elderly
Renal / hepatic impairment
Renal Impairment: Limited information
Hepatic Impairment: Limited information
Overdose effects
Symptoms: Limited information.
Treatment: Supportive care.
Storage conditions
Store in a dry place, away from light; keep out of reach of children.