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Company•Opsonin Pharma Limited

Acerux-H

5gm+1gm/100gmRx
Generic: Aciclovir 5% + Hydrocortisone 1% Topical

৳ 35/unit

Pack: ৳ 35

Cream5gm Tube
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At a glance

Aciclovir 5% + Hydrocortisone 1% Topical is a combination cream used for the early treatment of recurrent herpes labialis (cold sores). It reduces the likelihood of ulcerative cold sores and shortens lesion healing time.

Indications

Early treatment of recurrent herpes labialis (cold sores) in adults and children (6 years of age and older).

Pharmacology

Aciclovir is a synthetic purine nucleoside analogue with inhibitory activity against Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2). The inhibitory activity is highly selective due to its affinity for the HSV-encoded enzyme thymidine kinase (TK). This viral enzyme converts Aciclovir into Aciclovir monophosphate. The monophosphate is further converted into diphosphate by cellular guanylate kinase and into triphosphate by cellular enzymes. Aciclovir triphosphate stops herpes viral DNA replication through: 1) competitive inhibition of viral DNA polymerase, 2) incorporation into and termination of the growing viral DNA chain, and 3) inactivation of viral DNA polymerase. Hydrocortisone is the main glucocorticoid secreted by the adrenal cortex, used topically for its anti-inflammatory effects.

Dosage

Adults and children ≥6 years:

  • Apply cream to the affected area 5 times daily (approximately every 4 hours) for 5 days.
  • Initiate therapy as early as possible after the first signs and symptoms (e.g., tingling, itching, redness).
Side effects

Common side effects (<1%):

  • Skin drying or flaking
  • Burning or tingling sensation
  • Erythema (redness)
  • Pigmentation changes
  • Application site reactions (including signs of inflammation)
Use in pregnancy

Pregnancy Category: B. No adequate studies in pregnant women. Systemic exposure is minimal with topical use. Use only if clearly needed with medical advice.

Pregnancy Category: B — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Seek medical advice if cold sore fails to heal within 2 weeks.
  • Caution in immunocompromised patients.
  • Do not use in eyes, mouth, nose, or genitals.
  • Use with caution during pregnancy and lactation.
Overdose effects

Topical overdose is unlikely; excessive application may cause skin irritation.

Storage conditions

Store below 30°C in a cool and dry place, protected from light and moisture. Keep out of reach of children.

Aciclovir 5% + Hydrocortisone 1% Topical — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.