Acnetrin0.025%

Tretinoin Topical is a form of vitamin A that is used to treat acne which appears as spots or pimples on your face, chest or back. It also helps to smooth rough facial skin and to reduce fine wrinkles on the skin. Tretinoin Topical reduces excessive oil production of the skin. Ideally, a pinpoint application at nighttime is recommended for the duration prescribed by your doctor. The amount you need and for how long you need to take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of this medicine. Follow your doctor's instructions. You should not apply it to damaged or broken skin and avoid contact with your mouth, eyes and nose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. Consult your doctor again if you do not notice any improvement after a few weeks. Using more medicine or applying it more often than prescribed will not make it work any faster and may increase the side effects. The most common side effects include irritation, dryness and redness of the skin. They are usually mild and improve as your body gets used to the medicine. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips and eyes. Let your doctor know if these side effects bother you or do not go away. Serious side effects with this medicine are rare. This medicine may make you more sensitive to sunlight so you should limit exposure to the sun if possible. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. Pregnant women or women who are planning to get pregnant should not use this medicine as it can lead to birth defects. Tretinoin Topical is a form of vitamin A. When applied on skin, it reduces oil production in the skin, replenishes acne-prone skin and helps keep your pores open.

• Acne

Tretinoin is a trans-retinoic acid form of vitimin A. It stimulates mitosis and turnover of follicular epithelial cells and reduce their cohesiveness. This facilitates extrusion of existing comedones and prevents formation of new comedone. It also exhibits thinning effect on the stratum corneum. In acute promyelocytic leukaemia, it induces cellular differentiation and decreases proliferations.

Adult Dose: Topical/Cutaneous Acne vulgaris Adult: Apply once, usually at bedtime, onto affected area which has been previously cleansed to remove excessive oiliness and dried. Therapeutic response may be seen after 6-8 wk. Mottled hyperpigmentation, roughness and fine wrinkling of photodamaged skin Adult: Apply a pea-sized amount onto entire face once daily at night. Therapeutic response may be seen after 6 mth. Child Dose: Topical/Cutaneous Acne Vulgaris 12 years: Apply once, usually at bedtime, onto affected area

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

If you miss a dose of Tretinoin Topical, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Erythema (skin redness) • Skin irritation • Dry skin • Dry lips • Pale red skin • Increased sensitivity to light

No interaction found/established You have been prescribed Tretinoin Topical for the treatment of acne. Clean the affected area with water and a non-medicated soap. Let it dry for 20-30 minutes before applying Tretinoin Topical. It may increase the severity of the spots or pimples in the first few weeks of use. Continue using it as prescribed by your doctor. It may cause a stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists. Avoid exposure to sunlight while using Tretinoin Topical as it increases the sensitivity of your skin. Use protective measures such as sunscreen or protective clothing. Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile. Avoid taking tetracycline (e.g. doxycycline) as it may reduce the Tretinoin Topical activity. Do not use Tretinoin Topical if you are pregnant. Inform your doctor if excessive skin dryness or skin sensitivity take place.

Hypersensitivity to retinoids. Application to eczematous, sunburnt or abraded skin. Pregnancy, lactation.

Enhances percutaneous absorption of minoxidil. Increased risk of fatal thrombotic complications with antifibrinolytic. Increased tretinoin concentrations with azole antifungals. Enhances peeling action of sulphur, resorcinol, benzoyl peroxide, salicylic acid. Increased photosensitivity with photosensitising medications eg, thiazides, tetracyclines, fluoroquinolones, phenothiazines and sulfonamides. Potentially Fatal: Increased risk of intracranial pressure with tetracyclines.

No interaction found/established

[CONSULT YOUR DOCTOR] Tretinoin Topical may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Tretinoin Topical is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

No interaction found/established No interaction found/established

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