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At a glance

Magnesium Sulfate Heptahydrate is a magnesium salt used as an oral laxative for constipation and as an injection for eclampsia, pre-eclampsia, severe asthma, and magnesium deficiency.

Indications
  • Constipation (oral laxative)
  • Seizure prevention in eclampsia/pre-eclampsia (injection)
  • Severe asthma (injection)
  • Magnesium deficiency (injection)
Pharmacology

Magnesium sulfate draws water into the bowel through osmotic effect to soften stool and reduces neuromuscular over-excitability to prevent seizures.

Dosage

Constipation (Oral): 5-15 g dissolved in water

Injection: Hospital use only at physician-determined doses

Side effects

Oral: Diarrhea, abdominal cramps

Injection: Warmth, low blood pressure; excess causes breathing difficulty and loss of reflexes (magnesium toxicity)

Use in pregnancy

Use in Pregnancy: Used under supervision in eclampsia; otherwise use with caution. Category D - always consult a doctor before taking during pregnancy.

Pregnancy Category: D — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in kidney disease
  • Calcium gluconate is kept ready as an antidote during injection
  • Used under supervision in eclampsia
Overdose effects

Magnesium toxicity - breathing difficulty, loss of reflexes; treat with calcium gluconate and supportive care.

Storage conditions

Store below 30°C in a dry place.

Magnesium Sulfate Heptahydrate — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.