৳ 410/unit
Pack: ৳ 410
৳ 410/unit
Pack: ৳ 410
At a glance
Budesonide is an inhaled corticosteroid used for the long-term preventive treatment of asthma and COPD. It reduces inflammation in the lungs, widens the airways, and helps prevent asthma symptoms.
Indications
- Asthma - long-term preventive treatment
- Chronic Obstructive Pulmonary Disease (COPD)
Pharmacology
Budesonide is a corticosteroid that prevents the release of inflammatory chemical messengers in the lungs. It controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes and fibroblasts, and reverses capillary permeability and lysosomal stabilization to prevent and control inflammation. The drug is primarily metabolized in the liver by CYP3A4. The therapeutic effects of inhaled budesonide are largely explained by its direct local action on the respiratory tract.
Dosage
Adults (Inhaler): 1-2 inhalations twice daily. Some patients may require 4 inhalations twice daily.
Adults (Nebulizer solution): Severe asthma: 1-2 mg twice daily; Maintenance: 0.5-1 mg twice daily.
Children (2-12 years, Nebulizer): Initial: 0.5-1 mg twice daily; Maintenance: 0.25-0.5 mg twice daily.
Severe hepatic impairment: Avoid use. Moderate hepatic impairment: Reduce dose to 3 mg/day.
Note: Use the lowest effective dose. Continue regular use even if symptoms are controlled.
Side effects
Common side effects: Throat irritation, hoarseness, oral thrush (fungal infection in the mouth and throat), respiratory tract infection.
Long-term use: Adrenal gland suppression, osteoporosis, glaucoma or cataracts, growth delay in children.
Use in pregnancy
May be unsafe during pregnancy (Category C). Limited human studies available; animal studies have shown harmful effects on the developing baby. Consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Use the lowest effective dose to control asthma.
- Budesonide will not stop an ongoing asthma attack; use a rescue inhaler.
- Rinse your mouth after using the inhaler.
- Long-term use may require bone density and eye pressure tests.
- Risk of infection may increase.
- Inform your doctor if you have liver disease.
Overdose effects
Overdose may cause adrenal gland suppression, hypercorticism, and Cushing's syndrome. Consult your doctor if overdose is suspected.
Storage conditions
Store below 30°C in a dry place, away from light. Keep out of reach of children.