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At a glance

Gatifloxacin is an antibiotic used for the treatment of bacterial eye infections.

Indications
  • Bacterial conjunctivitis
  • Bacterial eye infections
Pharmacology

Gatifloxacin is an 8-methoxyfluoroquinolone anti-infective for topical ophthalmic use. The antibacterial action of Gatifloxacin results from inhibition of DNA gyrase and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.

Dosage

Gatifloxacin 0.3%:

  • Days 1 and 2: Instill one drop every two hours in the affected eye(s) while awake (up to 8 times daily)
  • Days 3 through 7: Instill one drop up to 4 times daily while awake

Gatifloxacin 0.5% (1+ years):

  • Day 1: Instill one drop every two hours while awake (up to 8 times)
  • Days 2 through 7: Instill one drop two to four times daily while awake

* Use as directed by the registered physician

Side effects

Common Side Effects:

  • Conjunctival irritation
  • Increased lacrimation
  • Burning sensation
Use in pregnancy

Use in Pregnancy: May be unsafe during pregnancy. Animal studies have shown harmful effects.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Precautions:

  • Do not wear contact lenses if you have signs of bacterial conjunctivitis.
  • Avoid contaminating the applicator tip with material from the eye, fingers or other source.
  • Apply pressure on the corner of the eye for about 1 minute after instilling.
  • Wait for 5-10 minutes before delivering the next medication.
Overdose effects

Overdose: An overdose of this medication is unlikely to threaten life.

Storage conditions

Storage: Protect from light. Store in cool and dry place. Do not use more than 4 weeks after opening. Keep out of reach of children.

Gatifloxacin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.