Amocal 5
Rx- Generic:
- Amlodipine Besilate
- Company:
- Opsonin Pharma Limited
- Dosage form:
- Tablet
- Pack size:
- Strip (14 Tablet)
৳ 5/unit
Pack: ৳ 70
Price comparison
- This brand
- ৳ 5
- Cheapest of this genericAlopin
- ৳ 1
The cheaper brand costs ৳ 4.00 less per unit
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At a glance
Amlodipine Besilate is a calcium channel blocker used to treat hypertension (high blood pressure) and angina (chest pain). It relaxes blood vessels and reduces the workload of the heart.
Indications
- Essential hypertension - alone or in combination with other antihypertensive agents
- Chronic stable angina pectoris - alone or in combination with other antianginal agents
- Vasospastic angina (Prinzmetal's or variant angina) - as monotherapy or in combination with other antianginal drugs
Dosage
Hypertension: 5 mg once daily (maximum 10 mg). Elderly and hepatic impairment patients may start with 2.5 mg once daily.
Angina (Chronic stable or Vasospastic): 5-10 mg daily (lower dose for elderly and hepatic impairment). Most patients require 10 mg.
Pediatric (6-17 years - hypertension): 2.5 mg once daily initial, up to 5 mg once daily after 4 weeks. Efficacy in children <6 years not established.
Hepatic Impairment: Severe hepatic impairment: start with 2.5 mg once daily and titrate slowly.
Renal Impairment: No dose adjustment needed (amlodipine is not dialyzable).
Side effects
- Fatigue
- Ankle swelling
- Sleepiness
- Dizziness
- Flushing
- Headache
- Nausea
- Palpitations
- Edema
- Abdominal pain
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
Rare: Increased angina, excessive hypotension, cerebral or myocardial ischemia, transient blindness, rash, fever, liver function abnormalities
Precautions & warnings
Serious Precautions:
- Patients with severe obstructive coronary artery disease may develop increased angina or MI when starting calcium channel blocker therapy or increasing dose
- Caution in severe aortic stenosis, hepatic impairment
- Caution in severe left ventricular dysfunction, sick-sinus syndrome, hypertrophic cardiomyopathy
- Heart failure patients may have increased risk of pulmonary edema
- Caution during pregnancy - animal studies have shown fetal risk
- Blood pressure may drop suddenly - rise slowly from sitting or lying position
- Caution while driving or operating machinery - may cause dizziness