osudhkosh

Ampirex IV/IM500mg

Rx
Generic:
Ampicillin
Company:
Jayson Pharmaceuticals Ltd.
Dosage form:
Injection
Pack size:
Injection
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৳ 22.49/unit

Pack: ৳ 22.49

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৳ 22.49
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৳ 20.43

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At a glance

Ampicillin is a penicillin-type antibiotic used to treat a variety of bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract (e.g. pneumonia), urinary tract, skin and soft tissue, and typhoid fever. Ampicillin is also used to prevent bacterial endocarditis in people with pre-existing heart disease.

Indications
  • Respiratory tract infections (pneumonia, bronchitis)
  • Ear, nose and sinus infections (otitis media, sinusitis)
  • Urinary tract infections (UTI)
  • Gastrointestinal infections (shigellosis, typhoid)
  • Skin and soft tissue infections
  • Gonorrhea
  • Meningitis
  • Listeriosis
  • Peritonitis
  • Endocarditis prophylaxis
  • Perinatal group B streptococcal infection prevention
Dosage

Adult Oral Dosage:

  • Biliary tract infections, bronchitis, endocarditis, gastroenteritis, listeriosis, otitis media, peritonitis: 0.25-1 g every 6 hours
  • Typhoid and paratyphoid fever (acute): 1-2 g every 6 hours (2 weeks)
  • Typhoid carriers: 1-2 g every 6 hours (4-12 weeks)
  • Uncomplicated gonorrhea: 2 g + probenecid 1 g (single dose), repeat recommended in females
  • Urinary tract infections: 500 mg every 8 hours

Adult Parenteral Dosage:

  • Susceptible infections: 500 mg every 6 hours (IM or slow IV injection)
  • Meningitis: 2 g every 6 hours (IV)
  • Septicemia: 150-200 mg/kg/day, IV for at least 3 days, then IM every 3-4 hours
  • Perinatal group B streptococcal infection prophylaxis: Initial 2 g IV, then 1 g every 4 hours until delivery

Pediatric Oral Dosage:

  • Under 10 years: Half of adult routine dosage
  • Weight-based: 50-100 mg/kg/day (every 6 hours), if >20 kg: 1-2 g/day (every 6 hours)

Pediatric Parenteral Dosage:

  • Susceptible infections: 50-200 mg/kg/day (every 6 hours)
  • Endocarditis/meningitis: 300-400 mg/kg/day (every 4-6 hours)

Intra-articular/Intraperitoneal/Intrapleural:

  • Adult: 500 mg daily
  • Child (under 10 years): Half of adult routine dosage

Renal Dose: Reduce dose or increase interval if CrCl <10 mL/min.

Group A β-hemolytic streptococci: At least 10 days treatment (to prevent acute rheumatic fever or glomerulonephritis).

Side effects
  • Rash (Erythematous maculo-papular rashes)
  • Vomiting
  • Allergic reactions
  • Nausea
  • Diarrhea
  • Sore mouth
  • Black/hairy tongue
  • Fever
  • Joint pains
  • Hemolytic anemia, thrombocytopenia, leukopenia, neutropenia
  • Interstitial nephritis, hepatitis, cholestatic jaundice
  • Anaphylaxis, Clostridium difficile-associated diarrhea (CDAD)
  • Stevens-Johnson syndrome, toxic epidermal necrolysis
Precautions & warnings

Important Precautions:

  • Inform your doctor if allergic to penicillin or cephalosporin antibiotics - serious anaphylactic reactions may occur
  • Complete the full course - do not stop even if you feel better
  • Stop and inform your doctor immediately if you develop allergic reactions (rash, swelling of face/throat/tongue, breathing difficulties)
  • Inform your doctor if you notice bloody stools or develop abdominal cramps
  • Caution in infectious mononucleosis
  • Caution in kidney disease
  • Caution during pregnancy and lactation
  • Caution in patients with β-lactam allergy history
Ampicillin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.