Antial 4
Rx- Generic:
- Galantamine
- Company:
- ACI Limited
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 12.05/unit
Pack: ৳ 12.05
At a glance
Galantamine — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Galantamine is used to treat mild to moderate dementia in Alzheimer’s disease, a progressive illness which gradually affects memory and thinking. It does not cure this illnesses but may help improve memory, awareness and other symptoms. Your doctor will explain how to take Galantamine and give you the one most suitable for you. Follow the instructions carefully to get the most benefit. The dose may change from time to time to suit your individual needs. You may take it with food, preferably at night before going to bed. It can take up to few weeks for symptoms to improve so keep taking your medicine regularly. You should not stop taking this medicine without consulting your doctor. Some common side effects of this medicine include diarrhea, nausea, vomiting, loss of appetite and weight loss. Some people may experience dizziness, increase in blood pressure or decreased heart rate. You may have side effects more often when you start your treatment or when your dose is increased. Usually, the side effects will slowly go away as your body gets used to the Galantamine. If they are severe or will not go away, you should contact your doctor. Before using Galantamine, you should tell your doctor if you have ever had heart problems, stomach ulcer, epilepsy or asthma. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. During pregnancy this medicine should only be taken if it is advised. Memory loss in Alzheimer’s disease occurs due to disturbances of signal transmission in the brain. Galantamine is a cholinesterase inhibitor. It works by increasing the levels of a chemical messenger (acetylcholine) involved in transmmission of nerve signals. This improves memory and thinking.
Indications
• Alzheimer's disease
Mechanism of action
Galantamine is a centrally-acting cholinesterase inhibitor, elevating acetylcholine in the cerebral cortex. Glutamine and serotonin levels may also be increase. It has nicotinic receptor agonist properties.
Dosage
Adult Dose: Alzheimer Disease Initial 4 mg PO q12hr Maintenance Titrate to 8-12 mg PO q12hr; increase by 4 mg q12hr at no less than 4 week intervals Hepatic Impairment Moderate: (Child-Pugh score 7-9): Not to exceed 16 mg/day Severe: Not recommended Child Dose: Not recommended Renal Dose: Renal Impairment Moderate: Not to exceed 16 mg/day Severe (CrCl <9 mL/min): Not recommended
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Galantamine is to be taken with food.
Missed dose
If you miss a dose of Galantamine, skip it and continue with your normal schedule. Do not double the dose.
Side effects
Common: • Nausea • Vomiting • Diarrhea
Precautions & warnings
[UNSAFE] Galantamine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Galantamine to slow down the progression of Alzheimer's disease. It does not cure Alzheimer's disease but may help improve brain function and ability to do daily activities. Take it with or without food, preferably at night before going to bed. It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Galantamine. Monitor your body weight regularly as both Galantamine and Alzheimer's disease can cause weight loss. Do not drive or do anything that requires mental focus until you know how Galantamine affects you. It may cause serious skin rashes. Stop taking medication and inform your doctor if you notice a skin rash. Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease. Inform your doctor about taking Galantamine, If you are going to have surgery under anesthesia. Be cautious while taking this medicine if you suffer from peptic ulcer as it may cause vomiting, stomach bleeding, stomach pain, or discomfort. Inform your doctor if you experience seizures or convulsions while taking this medicine.
Contraindications
Hypersensitivity; severe liver or kidney dysfunction; lactation; disorders of galactose metabolism; urinary retention or GI obstruction. Lactation.
Drug interactions
ncreased serum concentrations when used with drugs that inhibit CYP2D6 (e.g. quinidine, fluoxetine, fluvoxamine, and paroxetine) and CYP3A4 (e.g. ketoconazole and ritonavir). Cimetidine may increase the bioavailability of galantamine. Increased risk of gastric ulcer when used with NSAIDs. Potentially Fatal: Amiodarone, ?-blockers, diltiazem or verapamil; NSAIDs; digoxin.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Galantamine.
Use in pregnancy
[SAFE IF PRESCRIBED] Galantamine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[CONSULT YOUR DOCTOR] Galantamine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[CAUTION] Galantamine should be used with caution in patients with severe kidney disease. Dose adjustment of Galantamine may be needed. Please consult your doctor. However, use of this medicine is not recommended in patients with end-stage kidney disease. [CAUTION] Galantamine should be used with caution in patients with liver disease. Dose adjustment of Galantamine may be needed. Please consult your doctor. Use of Galantamine is not recommended in patients with severe liver disease.
Common questions
Why the failure of Alzheimer's therapy now a days??? as the disese mechanisms are still not defined in absolute terms; still PATIENT is needed and is ongoing Sir, My father ( an advocate) has developed symptoms of Alzheimer recently and sometimes he takes medicines on his own. He gets weak and unable to walk after taking tablets. Is there any test which can tell which medicines that he took? He takes Ayurved, Allopath, Homeopathy all and does not listen to me. Kindly help Dear Sir Thank you for consulting with me. Alzheimer's disease is a difficult disease to handle since patient develops dementia or forgetfulness. There are no blood tests which can tell you which medicines he took. Please consult a neurologist/ Psychiatrist I am suffering from alzehimer. I forget things like where I put key in morning. Some small things which makes me to suffer from condolence. What is the reason and how can I cure it ? Alzheimer's have many reasons which may be genetic, vitamins deficiency, hormonal problems, alcohol, other drugs, age related and others. We need to investigate you for finding cause. I strongly advice consultation with psychiatrist. If you are from Mumbai, see me.There is no cure to Alzheimer's, but we can suppress symptoms. Looking at your age, I am very much sure you are not suffering from Alzheimer's!!!! G-DON tablet is for what disease what is composition of gdon tablet I suffered from inflammatory bowel disease https://www.1mg.com/otc/jiva-digestol-tablet-otc329948One ?one tablet morning & evening after taking food , use at least 1-2 months Tablet in case fever for 8 months pregnancy Paracetamol or crocin tablets, 3- 4 times a day. what is the perfect tablet instead of MYTH-8? I don't know what is myth 8 Have pigmentation on face fr last 8 years Send me one photo of disease condition. So that i can suggest accordingly.