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At a glance

Amlexanox is an anti-aphthous ulcer medication used for the treatment of mouth ulcers. It reduces inflammation, relieves pain and promotes faster healing. It forms a protective film over the ulcer surface.

Indications

Mouth ulcers (aphthous ulcers/canker sores).

Pharmacology

Amlexanox accelerates the healing of aphthous ulcers. Although the exact mechanism is not fully known, in vitro studies have shown that Amlexanox is a potent inhibitor of the formation and/or release of inflammatory mediators (histamine and leukotrienes) from mast cells, neutrophils, and mononuclear cells. It adheres to the wet surfaces of the mouth and forms a protective film over the ulcer, speeding up the healing process.

Dosage

Adults: Apply directly to the ulcer 4 times daily (after breakfast, lunch, dinner and at bedtime after brushing teeth). Continue use until the ulcer heals completely or as directed by the physician.

Side effects

Common side effects: Mild pain, stinging or burning sensation at the application site, taste alteration.

Rare: Nausea, diarrhea, contact mucositis, skin rash.

Use in pregnancy

Pregnancy Category: B. Animal studies have shown low or no adverse effects on the fetus; human studies are limited. Use only if clearly needed with medical advice.

Pregnancy Category: B — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Wash hands before and after application
  • Avoid contact with eyes (rinse with plenty of water if contact occurs)
  • Consult a doctor if no significant improvement occurs within 10 days
  • Discontinue use if skin rash, new mouth ulcers or white patches appear
  • Efficacy has not been evaluated in immunocompromised patients
  • Use lower initial doses in elderly patients
Overdose effects

Topical overdose is unlikely; excessive application may cause local irritation.

Storage conditions

Store in a cool and dry place, protected from light. Keep out of reach of children.

Amlexanox — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.