Arolef100mg

Leflunomide is used in the treatment of rheumatoid arthritis and psoriatic arthritis. It helps in slowing down the progression of the disease and provide relief from pain, swelling, and redness. Leflunomide can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Using this medicine may cause some common side effects such as nausea, headache, dyspepsia, rash, diarrhea, increased liver enzymes, and respiratory tract infection. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms. To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor of all the other medicines you are taking. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or effecting your blood counts. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine. Leflunomide blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain autoimmune diseases. It suppresses the underlying disease process, rather than simply treating the disease.

• Rheumatoid arthritis • Psoriatic arthritis

Leflunomide is an immunomodulating agent and DMARD. It inhibits pyrimidine synthesis by inhibiting dihydroorotate dehydrogenase enzyme activity resulting in antiproliferative and anti-inflammatory effects.

Adult Dose: Oral Rheumatoid arthritis; Psoriatic arthritis Adult: Loading dose: 100 mg once daily for 3 days. Maintenance: 10-20 mg once daily. Hepatic impairment: Contraindicated. Child Dose: Safety and efficacy not established Renal Dose: Renal impairment: Mild: No dosage adjustment needed. Moderate to Severe: Contraindicated.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leflunomide may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Leflunomide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Nausea • Headache • Rash • Diarrhea • Increased liver enzymes • Respiratory tract infection

[UNSAFE] Leflunomide may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Leflunomide to control the symptoms and slow down the progression of rheumatoid arthritis. It will take 6-8 weeks for Leflunomide to work. Hence, keep taking the medicine. Get blood tests done every 4 weeks. This is to make sure that Leflunomide is not harming your liver or blood counts. Avoid alcohol when taking Leflunomide as it could harm your liver. Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Leflunomide. Leflunomide may increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses. Tell your doctor if you experience nausea or diarrhea.

Significant hepatic impairment, compromised immune function including bone marrow dysplasia or severe uncontrolled infection; concurrent vaccination with live vaccines. Pregnancy, lactation.

Cholestyramine and activated charcoal may decrease plasma concentration of active metabolite. Concurrent use of methotrexate and other hepatotoxic drugs may increase the risk of hepatotoxicity. Rifampicin increases serum levels of the active metabolite. Potentially Fatal: May enhance the adverse effects of live vaccines.

[UNSAFE] It is unsafe to consume alcohol with Leflunomide.

[UNSAFE] Leflunomide is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

[CONSULT YOUR DOCTOR] Leflunomide is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CAUTION] Leflunomide should be used with caution in patients with kidney disease. Dose adjustment of Leflunomide may be needed. Please consult your doctor. [UNSAFE] Leflunomide is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Suffering from rheumatoid arthritis Now she is medicating with lefno 20 mg n folitrax 20 mg Refer to a Rheumatologist Rheumatoid arthritis diseases attack Rheumatoid arthritis diseases tablet for this please consult rheumatologist for the same I have joint pain in my rt wrist since 6 yrs. What are the possible reasons? It may be Tenosynovitis, or Rheumatoid arthritis or any other type of arthritis Sir/Ma'am, I feel pain in the heel of both the legs especially when I get up from the bed in the morning. After walking couple of steps, it goes away. there is no bone problem reported in the Xray report. Please guide me what could be the reason? This is the test for rheumatoid arthritis What is gatheya. What is it solution It is supposed to be Rheumatoid Arthritis All bone are comptly stif and she couldn't move any were looks like rheumatoid arthritishave u been evaluated for it Hi , I am suffering from rheumatoid arthritis for many many years. I am on Medrol, folitrax, HCQS, lefno and calcium for 10 years. My ESR is always high. Please suggest that is there any alternate line of treatment available. Regards Yes Consult a Rheumatologist for the same