Arolef100mg
Rx- Generic:
- Leflunomide
- Company:
- General Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
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৳ 1/unit
Pack: ৳ 1
At a glance
Leflunomide is used in the treatment of rheumatoid arthritis and psoriatic arthritis. It slows down disease progression and provides relief from pain, swelling, and redness. It is an immunomodulating agent and DMARD.
Indications
- Active rheumatoid arthritis (RA) - reducing signs and symptoms and structural damage
- Psoriatic arthritis
Dosage
Adult Dose (Oral):
- Loading dose: 100 mg once daily for 3 days
- Maintenance dose: 10-20 mg once daily
- May be reduced to 10 mg daily if tolerability issues arise
Hepatic Impairment: Contraindicated
Renal Impairment: Mild: No dose adjustment; Moderate-Severe: Contraindicated
Side effects
Common Side Effects:
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Respiratory infection
- Bronchitis
- Elevated liver enzymes
- Aggravation of pre-existing hypertension
- Alopecia
- Rash
Precautions & warnings
- Highly unsafe during pregnancy - avoid pregnancy
- Do not use during breastfeeding
- Monitor liver function before and during treatment
- Avoid alcohol (risk of liver damage)
- Increased risk of infection - avoid close contact with people with cold or flu
- Caution when driving or activities requiring concentration (may cause dizziness or drowsiness)
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.