Asunra 100
Rx- Generic:
- Deferasirox
- Company:
- Nevian Lifescience PLC
- Dosage form:
- Tablet
- Pack size:
- Strip (6 Tablet)
৳ 50/unit
Pack: ৳ 300
At a glance
Deferasirox is an oral iron chelator used for the treatment of chronic iron overload caused by repeated blood transfusions.
Indications
- Chronic iron overload due to repeated blood transfusions
- Transfusion-dependent thalassemia
- Sickle cell disease and myelodysplastic syndrome
Dosage
Adult - Transfusional Hemosiderosis: 20 mg/kg once daily orally; may increase by 5-10 mg based on serum ferritin; maximum 40 mg/kg/day.
Adult - Nontransfusion-Dependent Thalassemia: 10 mg/kg once daily.
Side effects
Common: Nausea, headache, vomiting, rash, abdominal pain, constipation, itching, increased liver enzymes, abdominal distension, diarrhea.
Serious: Cytopenias, gastrointestinal ulceration and hemorrhage, Stevens-Johnson syndrome (SJS), auditory and ocular disturbances.
Precautions & warnings
Gastrointestinal bleeding, ulceration and irritation may occur; caution with NSAIDs, corticosteroids, oral bisphosphonates and anticoagulants. Monitor blood counts. Discontinue if serious hypersensitivity reactions occur. Caution while driving (drowsiness, dizziness).