৳ 80.30/unit
Pack: ৳ 80.30
৳ 80.30/unit
Pack: ৳ 80.30
At a glance
Tacrolimus 0.1% & 0.03% Topical Ointment is used for moderate to severe atopic dermatitis (eczema) and other skin conditions, particularly when conventional therapies are inadvisable or inadequate.
Indications
- Moderate to severe atopic dermatitis (eczema)
- Allergic contact dermatitis
- Psoriasis
- Vitiligo
- Lichen planus
- Seborrheic dermatitis
- Pemphigus vulgaris
- Chronic cutaneous graft-versus-host disease
Pharmacology
Tacrolimus binds to FKBP-12, inhibiting calcineurin phosphatase activity, preventing NF-AT dephosphorylation and translocation, and reducing cytokine production. It inhibits T-lymphocyte activation, reducing the inflammatory cascade and relieving skin inflammation and itching.
Dosage
Adult Dose (Topical):
- Apply a thin layer of 0.03% or 0.1% ointment to affected areas twice daily
- Rub in gently and completely
- For short-term and intermittent use only
Pediatric Dose (Topical):
- ≥2 years: 0.03% ointment twice daily
- ≥16 years: 0.1% ointment may be used
Side effects
Common Side Effects:
- Application site burning, irritation, itching, and redness
- Skin erythema
- Flu-like symptoms
- Headache
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in patients with skin infections
- Safety not established in generalized erythroderma
- Avoid continuous long-term use
- Caution in pregnancy and lactation
Overdose effects
Accidental oral ingestion may cause systemic tacrolimus side effects; seek medical advice.
Storage conditions
Store below 30°C; keep away from light; keep out of reach of children.