৳ 2.51/unit
Pack: ৳ 2.51
৳ 2.51/unit
Pack: ৳ 2.51
At a glance
Paracetamol + Caffeine is a combination medicine used for headache, migraine, toothache, neuralgia, fever, period pain, sore throat, backache and aches of colds and flu. Paracetamol provides analgesic and antipyretic effects while caffeine enhances pain tolerance.
Indications
- Headache
- Migraine
- Toothache
- Neuralgia
- Fever
- Period pain
- Sore throat
- Backache
- Aches and pain of colds and flu
Pharmacology
Paracetamol reduces pain and fever by inhibiting prostaglandin synthesis. Caffeine increases paracetamol solubility and absorption, enhances pain tolerance and threshold, and raises brain vascular tone to help in migraine.
Dosage
Adult Dose (Oral):
- 1-2 tablets every 4-6 hours
- Maximum daily: 8 tablets
Pediatric Dose: Not recommended for children below 12 years
Side effects
Common Side Effects:
- Increased heart rate
- Restlessness
- Thrombocytopenia
- Leukopenia
- Pancytopenia
- Neutropenia
- Agranulocytosis
- Pancreatitis
- Skin rashes
- Allergic reactions
Use in pregnancy
Use in Pregnancy: Paracetamol + Caffeine may be unsafe during pregnancy; animal studies show evidence of fetal harm.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in hepatic or renal failure
- Caution in patients taking other hepatotoxic medications
- Avoid prolonged use without consulting physician
- Caution while driving (may cause drowsiness and dizziness)
- Avoid alcohol
Overdose effects
Overdose (first 24 hours): Pallor, nausea, vomiting, anorexia, abdominal pain; liver damage may appear 12-40 hours after ingestion; glucose metabolism abnormalities and metabolic acidosis may occur.
Storage conditions
Store in a cool and dry place, protect from light and moisture; keep out of reach of children.