Atosiban EVER IV Infusion 5ml
37.5mg/5mlRx৳ 4,000/unit
Pack: ৳ 4,000
৳ 4,000/unit
Pack: ৳ 4,000
At a glance
Atosiban Acetate is an oxytocin receptor antagonist used intravenously to delay imminent preterm labor in pregnant women between 24 and 33 weeks of gestation.
Indications
To delay imminent pre-term birth in pregnant adult women with regular uterine contractions, cervical dilation of 1-3 cm, and gestational age from 24 to 33 completed weeks.
Pharmacology
Binds to myometrial oxytocin receptors, acting as a Gq antagonist to prevent intracellular calcium increase and subsequent uterine contractions.
Dosage
Administered intravenously in three stages: initial bolus (6.75 mg), loading infusion (300 mcg/min for 3 hours), followed by subsequent infusion (100 mcg/min up to 45 hours). Total duration not to exceed 48 hours.
Side effects
Nausea (very common); headache, dizziness, flushing, vomiting, tachycardia, hypotension, injection site reactions, hyperglycemia (common); fever, insomnia, pruritus, rash (uncommon).
Use in pregnancy
Indicated specifically for use between 24-33 weeks gestation under strict medical protocols.
Pregnancy Category: Category D / Restricted — always consult a doctor before taking during pregnancy.
Precautions & warnings
Use with caution in multiple pregnancies, hepatic impairment, or when premature membrane rupture cannot be excluded.
Overdose effects
Manage symptomatically under medical supervision.
Storage conditions
Store in a refrigerator (2°C-8°C). Keep away from light & moisture. Keep out of the reach of children.