osudhkosh
New
Company•Synovia Pharma PLC.

Avomine

25mgOTC
Generic: Promethazine Theoclate

৳ 1/unit

Pack: ৳ 1

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At a glance

Promethazine Theoclate is an anti-emetic drug used to prevent and treat nausea and vomiting, including travel sickness, and vertigo. It works by blocking histamine receptors in the vomiting center of the brain.

Indications
  • Prevention and treatment of nausea and vomiting (including travel sickness)
  • Vertigo
  • Post-operative nausea
Pharmacology

Promethazine Theoclate blocks histamine receptors in the vomiting center of the brain. The vomiting center is activated by nerve messages from the vestibular apparatus and causes nausea and vomiting. By blocking H1 receptors, it prevents middle ear disturbances from activating the vomiting center.

Dosage

Adult Dose (Oral):

  • Nausea/vomiting: 25 mg at night; may increase to 50-75 mg at night or 25 mg 2-3 times daily; max 100 mg daily
  • Motion sickness prophylaxis: 25 mg at night or 1-2 hours before travel

Pediatric Dose (Oral):

  • Nausea/vomiting (5-10 years): 12.5-37.5 mg daily
  • Motion sickness (5-10 years): 12.5 mg daily (at night or 1-2 hours before travel)
Side effects

Side Effects:

  • Dry mouth
  • Blurred vision
  • Headache
  • Dizziness
  • Drowsiness
  • Extrapyramidal effects (muscle spasms, tic-like movements of head and face)
  • Anaphylaxis
  • Jaundice
  • Blood dyscrasias
  • Photosensitivity
Use in pregnancy

Use in Pregnancy: May be unsafe during pregnancy; animal studies have shown harmful effects; use only if clearly needed.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • May affect driving ability; do not drive if drowsy or dizzy
  • Avoid alcohol (excessive drowsiness)
  • May increase sensitivity to sunlight; use sunscreen
  • Do not use for more than 7 days
  • Discontinue 72 hours before allergy testing
Overdose effects

Overdose: Children: excitation, ataxia, athetosis, hallucinations; Adults: drowsiness, coma; convulsions may occur; treatment: ipecacuanha or gastric lavage, supportive care, diazepam for convulsions.

Storage conditions

Protect from light; do not use after expiry date; keep out of reach of children.

Promethazine Theoclate — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.