৳ 180/unit
Pack: ৳ 180
৳ 180/unit
Pack: ৳ 180
At a glance
Azelastine Hydrochloride is an antihistamine medication used for the treatment of sneezing, runny or stuffy nose caused by allergies (allergic rhinitis) and allergic conjunctivitis. It works by blocking the effects of histamine, a chemical messenger responsible for allergic symptoms.
Indications
- Seasonal allergic rhinitis - adults and pediatric patients 5 years and older
- Vasomotor rhinitis - adults and adolescent patients 12 years and older
- Seasonal allergic conjunctivitis - adults and children 4 years and older
- Non-seasonal (perennial) allergic conjunctivitis - adults and children 12 years and older
Pharmacology
Azelastine, a phthalazinone derivative, is classified as a potent long-acting anti-allergic compound with selective H1 antagonist properties. An additional anti-inflammatory effect could be detected after topical ocular administration.
Data from in vivo (pre-clinical) and in vitro studies show that Azelastine inhibits the synthesis or release of the chemical mediators known to be involved in early and late stage allergic reactions (e.g., leukotriene, histamine, PAF and serotonin).
Dosage
Nasal Spray:
- Seasonal Allergic Rhinitis (Adults & 12+ years): 1-2 sprays per nostril twice daily
- Seasonal Allergic Rhinitis (5-11 years): 1 spray per nostril twice daily
- Vasomotor Rhinitis (Adults & 12+ years): 2 sprays per nostril twice daily
Eye Drop:
- Seasonal Allergic Conjunctivitis (Adults & 4+ years): 1 drop in each eye twice daily (up to 4 times daily if needed)
- Non-seasonal Allergic Conjunctivitis (Adults & 12+ years): 1 drop in each eye twice daily (up to 4 times daily if needed)
- Duration: Maximum 6 weeks; consult doctor if no improvement in 48 hours
Side effects
- Dysgeusia (bitter taste)
- Headache
- Dizziness
- Somnolence
- Epistaxis (nosebleeds)
- Nasal stinging or itching
- Dry mouth
- Sore throat
- Nausea
Use in pregnancy
[CONSULT YOUR DOCTOR] The effects of Azelastine during pregnancy have not been adequately studied. Use only if potential benefit justifies the potential risk to the fetus.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution when driving or operating machinery (may cause somnolence or dizziness)
- Avoid alcohol or other CNS depressants
- Avoid use in patients with recent nasal ulcers, nasal surgery, or nasal trauma
- Avoid spraying into the eyes
- Do not share the bottle with others
- Consult your doctor during pregnancy and breastfeeding
Overdose effects
Azelastine overdose may cause increased somnolence. Supportive therapy is recommended.
Storage conditions
Keep out of reach of children. Store below 30°C, in a cool and dry place, protected from light. Do not freeze.