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At a glance

Mirabegron is a beta-3 receptor agonist used for the treatment of overactive bladder symptoms.

Indications
  • Overactive bladder (OAB)
  • Urinary urgency
  • Increased urinary frequency
  • Urinary incontinence
Pharmacology

Mirabegron activates beta-3 adrenergic receptors increasing cyclic AMP and relaxing detrusor smooth muscle.

Dosage

Adult Dose (Oral):

  • Initial Dose: 25 mg once daily
  • Maintenance Dose: 25-50 mg once daily
  • Hepatic Impairment (Moderate): Not to exceed 25 mg/day
  • Renal Impairment (Severe): Not to exceed 25 mg/day
Side effects

Common Side Effects:

  • Hypertension
  • Headache
  • Nasopharyngitis
  • Urinary tract infection
  • Constipation
  • Tachycardia
Use in pregnancy

Use in Pregnancy: Possibly unsafe. Animal studies show reproductive toxicity.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Monitor blood pressure regularly
  • Contraindicated in severe uncontrolled hypertension
  • Not recommended in severe hepatic impairment
  • Caution in pregnancy and lactation
Overdose effects

Overdose may cause palpitations and increased heart rate (>100 bpm).

Storage conditions

Store in a cool and dry place protected from light.

Mirabegron — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.