Bicalon50mg
Rx- Generic:
- Bicalutamide
- Company:
- Drug International Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (14 Tablet)
৳ 30/unit
Pack: ৳ 420
At a glance
Bicalutamide — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Bicalutamide is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone. Bicalutamide should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Anemia (low number of red blood cells) is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes are some side effects which require immediate action. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out. Before taking it, tell your doctor if have diabetes, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment. Bicalutamide blocks the effect of the natural male hormones on the growth of prostate cells. Bicalutamide also blocks the undesired effects of androgens in females such as excessive hair growth and acne.
Indications
• Prostate cancer
Mechanism of action
Bicalutamide competes with androgen for the binding of androgen receptors, consequently blocking the action of androgens of adrenal and testicular origin, thus preventing the growth of normal and malignant prostatic tissue.
Dosage
Adult Dose: Oral Palliative treatment of advanced prostate cancer Adult: When used with gonadorelin analogue: Usual dose: 50 mg once daily. May be started with or at least 3 days before starting gonadorelin analogue therapy. Monotherapy or adjuvant therapy to surgery or radiotherapy in locally advanced prostatic cancer Adult: 150 mg once daily.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bicalutamide may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Anemia (low number of red blood cells) • Rash • Abdominal pain • Breast enlargement in male • Breast tenderness • Constipation • Decreased appetite • Decreased libido • Depression • Dizziness • Indigestion • Flatulence • Hot flashes • Increased liver enzymes • Nausea • Sleepiness • Weakness • Weight gain
Precautions & warnings
[SAFE] Bicalutamide does not usually affect your ability to drive. You have been prescribed Bicalutamide for the treatment of prostate cancer. Take it with or without food, preferably at the same time every day. It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors. If you are diabetic, monitor your blood glucose regularly while taking Bicalutamide. Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. Do not stop taking the medication without talking to your doctor first.
Contraindications
Hypersensitivity. Females, children. Pregnancy, lactation.
Drug interactions
Enhances effect of coumarin anticoagulants.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Bicalutamide. Please consult your doctor.
Use in pregnancy
[UNSAFE] Bicalutamide is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Use in lactation
[CONSULT YOUR DOCTOR] Information regarding the use of Bicalutamide during breastfeeding is not available. Please consult your doctor.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Bicalutamide is safe to use in patients with kidney disease. No dose adjustment of Bicalutamide is recommended. [CAUTION] Bicalutamide should be used with caution in patients with liver disease. Dose adjustment of Bicalutamide may be needed. Please consult your doctor. Regular monitoring of liver function tests is advisable while you are taking this medicine.
Common questions
Is this can be taken as a substitute for calutide-50 ? Sir, this is a drug for Prostate cancer. Can you share your reports, so that I can help you with some alternate treatment I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer. May not be prostate cancer, it is only begnin enlargement of prostate. Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless. Not a symptom of prostate cancer I am a patient of Prostate cancer, surgery in Oct 2014,testicles were removed. Till Feb 2016 PSA level was under control. I was using Calutide50,Urimax, Shelcal&Autrin, but after Feb, it started rising &went upto 66.Nuclear test in March ,Doctor told that cancer was spreading &changed Calutide by XBIRA250.PSA level has slightly decreased ,but whenever I go to urinate, I feel pain & too much pain above foot & in between knees. Pain is so much that it is very difficult to move even 10 to 15 mts.Please advice me U will require clinical evaluation.kindly show to urologist nearby. U can come to delhi to show me Protest cancer and problems with urine. PSA report is normal For prostate cancer need to consult your local area ayurvedic doctor. What is Nodular hyperlasia prostate This is not a cancerOnly increase in size of prostate Patient is suffering from prostate cancer please consult a medical oncologist