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At a glance

Silymarin [Milk thistle] is a flavonoid used for the treatment of jaundice, chronic inflammatory liver disease, hepatic cirrhosis, and alcoholic liver damage. It exhibits antioxidant, anti-inflammatory, and antifibrotic properties.

Indications
  • Jaundice
  • Chronic inflammatory liver conditions
  • Hepatic cirrhosis
  • Alcoholic liver damage
Pharmacology

Silymarin increases liver cell regeneration by enhancing DNA and RNA synthesis, stabilizes the hepatocyte external membrane to prevent toxin entry, scavenges free radicals, increases glutathione content to inhibit lipid peroxidation, and modifies ABC transporters, OATP, bile salt export pump, and TNF-α-dependent transporters.

Dosage

Adult Dose (Oral):

  • 1-3 capsules 2-3 times daily
  • Continue until symptom relief
Side effects

Side Effects:

  • Mild digestive upset
  • Allergic reactions
Use in pregnancy

Use in Pregnancy: Long-term safety studies are lacking; not recommended during pregnancy; consult your doctor.

Pregnancy Category: B — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Do not use if hypersensitive to any ingredient
  • Caution in pregnancy and lactation
  • Caution in kidney and liver disease
Overdose effects

No overdose information available; consult your doctor if overused.

Storage conditions

Store in a cool and dry place, away from light and moisture; keep out of reach of children.

Silymarin [Milk thistle] — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.