osudhkosh
New
Company•Gaco Pharmaceuticals(G.A Company Ltd)

Boxitrol

Rx
Generic: Bacitracin Zinc + Neomycin Sulphate + Polymixin B Eye prep

৳ 30/unit

Pack: ৳ 30

Eye Drop5ml drop
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At a glance

Bacitracin Zinc + Neomycin Sulphate + Polymixin B Eye prep is a combination antibiotic used for the treatment of bacterial eye infections. It is effective against both gram-positive and gram-negative bacteria.

Indications
  • Bacterial eye infections (blepharitis, conjunctivitis, keratitis)
  • Post-operative infection prevention
  • Neonatal eye infections
Pharmacology

Neomycin is an aminoglycoside antibiotic that binds to the 30S subunit of the bacterial ribosome, inhibiting protein synthesis and disrupting DNA synthesis. It is active against gram-negative aerobes and some strains of staphylococci.

Bacitracin inhibits bacterial cell wall peptidoglycan synthesis and is active against gram-positive bacteria (staphylococci, streptococci, corynebacteria, clostridia) and some gram-negative species (Neisseria and Haemophilus influenzae).

Polymyxin B binds to membrane phospholipids, disrupting the bacterial cytoplasmic membrane of most gram-negative organisms, allowing leakage of intracellular constituents.

Dosage

Adults and Children:

  • Eye Drops: 1-2 drops 3-4 times daily
  • Eye Ointment: Apply ½ inch ribbon to conjunctival sac of affected eye(s) every 3-4 hours for 7-10 days (for acute infections)
Side effects
  • Rash
  • Itching
  • Burning sensation
  • Anaphylactic reactions
  • Swelling
  • Conjunctival erythema
Use in pregnancy

[CONSULT YOUR DOCTOR] Limited safety data during pregnancy (Category C). Use only if clearly needed and under medical supervision.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Excessive use may lead to systemic absorption causing nephrotoxicity (polymyxin B sulfate) and neurotoxicity (bacitracin)
  • Prolonged use may cause overgrowth of non-susceptible organisms, including fungi
  • Consult doctor before use if wearing contact lenses
  • Caution during pregnancy and lactation
Overdose effects

Overuse may cause systemic absorption and toxicity. Consult a doctor if symptoms occur.

Storage conditions

Store in a cool and dry place, protected from light. Keep out of reach of children.

Bacitracin Zinc + Neomycin Sulphate + Polymixin B Eye prep — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.