Bromodel2.5mg
Rx- Generic:
- Bromocriptine
- Company:
- Opsonin Pharma Limited
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 12/unit
Pack: ৳ 120
At a glance
Bromocriptine — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Bromocriptine is a dopamine agonists and prolactin inhibitors. It is used in the treatment of medical condition occurs as of high level of prolactin such as infertility, or abnormal production of breast milk. Bromocriptine should be taken with food, but take it at the same time every day for better results. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Perform regular exercise, follow a diet plan and take other prescribed diabetes medicine while on treatment with this medicine. The most common side effects of this medicine include nausea, vomiting, headache, fatigue, and hypoglycemia (low blood sugar level). If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Always carry some sugar candy with you to overcome low blood sugar levels. You should avoid drinking alcohol as it can enhance medicine side effects. Before taking this medicine, tell your doctor if you have ever had liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Bromocriptine is a dopamine receptor agonist. It decreases the release of prolactin (milk hormone) in the body. Overproduction of this hormone is associated with abnormal production of breast milk as well as suppression of the sexual glands which can cause infertility. Reducing prolactin levels with Bromocriptine can therefore improve these conditions. In acromegaly, it works by lowering the amount of growth hormone in the body.
Indications
• High levels of prolactin • Female infertility • Acromegaly
Mechanism of action
Bromocriptine is a dopamine D2 and D3-agonist which works by activating postsynaptic dopamine receptors in the tuberoinfundibular and nigrostriatal pathways. It also inhibits the secretion of prolactin from the anterior pituitary and is used in the treatment of prolactinoma and in endocrinological disorders.
Dosage
Adult Dose: Adult: PO Parkinson's disease As adjunct to levodopa: 1st wk: 1-1.25 mg at night, 2nd wk: 2-2.5 mg at night; 3rd wk: 2.5 mg twice daily; 4th wk: 2.5 mg 3 times/day, then increase as needed. Maintenance: 10-40 mg/day. Hyperprolactinemia Initial: 1.25-2.5 mg PO qDay May increase by 2.5 mg/day q2-7Days Usual therapeutic dosage 5-7.5 mg/day, ranges from 2.5-15 mg/day Up to 30 mg/day has been used in some patients with amenorrhea &/or galactorrhea Acromegaly (Parlodel) 1.25-2.5 mg PO qHS for 3 days May increase by 1.25-2.5 mg/day at q3-7Days Not to exceed 100 mg/day Adjunct to surgery and radiotherapy in patients w/ acromegaly Initial: 2.5 mg twice daily, increase slowly, up to 5 mg 6 hrly if needed. Lactation suppression 2.5 mg/day for 2-3 days, up to 2.5 mg twice daily for 14 days. Prevention of puerperal lactation 2.5 mg on the day of delivery, then 2.5 mg twice daily for 14 days. Cyclical benign breast and menstrual disorders 2.5 mg twice daily. Hepatic Impairment: Dose adjustment may be necessary; there are no guidelines Child Dose: Hyperprolactinemia 11-15 years: 1.25-2.5 mg PO qDay (initially) Maintenance: 2.5-10 mg/day
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bromocriptine is to be taken with food.
Side effects
Common: • Nausea • Vomiting • Headache • Dizziness • Fatigue
Precautions & warnings
[CAUTION] Bromocriptine may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur. Bromocriptine is used to treat conditions caused by excess production of a natural hormone called prolactin such as infertility, or abnormal production of breast milk (galactorrhoea). It should be taken with or after food to avoid side effects such as nausea or indigestion. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Use caution while driving or doing anything that requires concentration as Bromocriptine can cause dizziness and sleepiness. Do not take Bromocriptine if you are breastfeeding. Monitoring of blood pressure may be advised regularly during treatment with Bromocriptine.
Contraindications
Breast carcinoma, hypersensitivity to ergot alkaloids, uncontrolled hypertension, severe ischaemic heart disease. Pregnancy and lactation.
Drug interactions
Bioavailability increased if given along with erythromycin. Alcohol reduces tolerance to bromocriptine and vice-versa. Effects of antihypertensives may be potentiated. Avoid concurrent psychotropics.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Bromocriptine.
Use in pregnancy
[SAFE IF PRESCRIBED] Bromocriptine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[CONSULT YOUR DOCTOR] Bromocriptine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Bromocriptine is usually not used during breastfeeding because it suppresses lactation.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Bromocriptine is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Bromocriptine may not be needed in these patients. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Bromocriptine in patients with liver disease. Please consult your doctor. However, a cautious use of this medicine is advised in these patients.
Common questions
How to overcome the side effects of Sicriptin I wanted to stop breast feeding. So i take sicriptin. But i suffered from heavy fever, wheezing, giddiness, black patches in skin. Kindly tell the solution You could be allergic to the medicine. Don't take it and consult a physician. For stopping breast feeding stop it gradually. Don't let your breast become engorged at any time. If it gets engorged then express a little bit of milk. But don't express too much. I am 25 years,married 1year back,not using any contraception,urine pregnancy test negative ,my periods are irregular .they were irregular since the beginning,usually lasts for 7_8days repeating on 1_2 months interval my last menses was on August 10th.i have done usg scan 6months back.and it was normal. Serum prolactin -39.75 TSH-5.44 HB-12.8 Both prolactin and tsh levels are high result ing in irregular periods and infertility. See a physician regarding treatment I am a 30 year old unmarried girl, my breasts size is 36, now the size of my breasts is 34 and release some drops of milk It seems your prolactin level is high. Kindly get a perm prolactin levels done Hi my wife PATIENT suffering from pcod and we are having problems to conceive. Pls suggest. She is having high amt of hair loss Pls find her reports for hair loss consult a dermatologisther prolactin is high so plz get a pooled prolactin levels done Cholesterol levels is high . How to maintain? Avoid oily food, do physical exercise, take sudh guggul 2 tablet twive Wat r investigation for infertility Hi PATIENT for ovarian follicles, CBC, TSH, Prolactin, Serum Progesterone, LH and FSH, Semen analysis, are normally required Depending on the case Hsg as well as laparoscopy may be required. Infertility problem. Taking treatment since may13. Did all test, iui, laparoscopy. said it's unexplained infertility. Hi PATIENT to 1mgd0ctors. Dorry to hear about your problem. Unexplained infertility is rising rapidly these days due to the high stress levels in our lives. I would suggest you continue taking treatment and I'm sure you will get a good news soon. All the best. Let me know if i can assist you in any way. Low sperm quality & infertility Take moosli Pak 1 spoon twice with milk, speman tablet 2 tablet twice with milk, chandraprabha vati 2 tablet twice