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Hyoscine Butyl Bromide is used in the treatment of pain due to smooth muscle spasm. It relieves cramps in the stomach, intestine, bladder, and ureter. It also be used to relieve the symptoms of Irritable Bowel Syndrome (symptoms include abdominal pain, cramping, bloating, and diarrhea or constipation). Hyoscine Butyl Bromide is given by your doctor or nurse. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effects are blurred vision, increased heart rate, dryness in mouth, and dilatation of pupil. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Pregnant women should also consult their doctor before taking this medicine. Hyoscine Butyl Bromide should be used with caution in patients with liver and kidney disease or alcohol abuse. Hyoscine Butyl Bromide is an anticholinergic medication. It works by relaxing the muscles in the stomach and gut (intestine). It stops sudden muscle contractions (spasms), thereby relieving cramps, pain, bloating, and discomfort.

• Pain due to smooth muscle spasm

Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.

Adult Dose: Oral Gastrointestinal tract spasm; Genitourinary spasm Adult: 20 mg 4 times daily. Parenteral Gastrointestinal tract spasm; Genitourinary spasm Adult: 20 mg IM/IV repeated after 30 min if needed. Max Dosage: 100 mg daily. Child Dose: Oral Gastrointestinal tract spasm; Genitourinary spasm Child: 6-12 yr: 10 mg tid.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

If you miss a dose of Hyoscine Butyl Bromide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Blurred vision • Increased heart rate • Dryness in mouth • Diarrhea • Dilatation of pupil

[UNSAFE] Hyoscine Butyl Bromide may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Do not take hyoscine if you are allergic to hyoscine or any of the other ingredient of the tablet or solution. Do not drive or operate machinery immediately after taking hyoscine as it may cause drowsiness. Consult your doctor before taking hyoscine, if you have a history of heart problems like heart failure or fast heart rate; an overactive thyroid; fever, constipation or difficulty while urinating.

Narrow-angle glaucoma, acute haemorrhage, paralytic ileus, tachycardia due to cardiac insufficiency, myasthenia gravis.

Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine). Potentially Fatal: Effect potentiated by other anticholinergic drugs and TCAs.

[UNSAFE] Hyoscine Butyl Bromide may cause excessive drowsiness with alcohol.

[CONSULT YOUR DOCTOR] Hyoscine Butyl Bromide may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Hyoscine Butyl Bromide is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Single dose is unlikely to interfere with breastfeeding, milk secretion may decrease during long-term use.

[CAUTION] Hyoscine Butyl Bromide should be used with caution in patients with kidney disease. Dose adjustment of Hyoscine Butyl Bromide may be needed. Please consult your doctor. [CAUTION] Hyoscine Butyl Bromide should be used with caution in patients with liver disease. Dose adjustment of Hyoscine Butyl Bromide may be needed. Please consult your doctor.

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