Canaglif 100

Canagliflozin is used alone or in combination with other medicines to treat type 2 diabetes mellitus. It helps control the high blood sugar levels seen in diabetes. This reduces the chances of serious complications of diabetes and also helps prevent heart disease. Canagliflozin can be taken with or without food at any time of day but you should try to take it at the same time every day. The dose will be decided by your doctor. Do not stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise and weight reduction as advised by your doctor. The most common side effects of this medicine include frequent urge to urinate, urinary tract infections, hypoglycemia (low blood sugar levels)and genital tract infection. It may cause the body to lose too much water. Drinking plenty of fluids to prevent dehydration. Some people may develop fungal infections in the genital area. Maintaining good hygiene can help prevent this. Before taking this medicine, inform your doctor if you have any kidney or liver problems or a urinary tract infection or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Monitor your blood sugar levels regularly while taking this medicine. Canagliflozin is an anti-diabetic medication. It works by removing excess sugar from your body through urine.

• Type 2 diabetes mellitus

Sodium-glucose co-transporter 2 SGLT-2 inhibition lowers the renal glucose threshold (ie, the plasma glucose concentration which exceed the maximum glucose reabsorption capacity of the kidney); lowering the renal glucose threshold results in increased urinary glucose excretion.

Adult Dose: Adults >18 years: Recommended Dose: 100 mg PO once daily taken before the first meal of the day May increase dose to 300 mg once daily in patients tolerating 100 mg/day who have an eGFR >60 mL/min/1.73 m² and require additional glycemic control. Elderly: In patients >75 years, the starting dose is 100 mg once daily. Renal Dose: Renal impairment eGFR >60 mL/min/1.73 m²: No dosage adjustment required eGFR 45 to <60 mL/min/1.73 m²: Do not exceed 100 mg/day eGFR <45 mL/min/1.73 m²: Do not initiate canagliflozin Discontinue if eGFR declines below 45 mL/min/1.73 m²

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Canagliflozin is to be taken empty stomach.

If you miss a dose of Canagliflozin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Frequent urge to urinate • Urinary tract infection • Increased thirst • Nausea

[CAUTION] Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur. Canagliflozin is used alone or together with other diabetes medicines to control blood sugar and avoid long-term complications. It may cause your body to lose too much fluid (dehydration) or you may urinate more often. Drink plenty of water and stay hydrated. It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety. It can cause genital fungal and/or urinary tract infections (UTIs) in both females and males, so practice good hygiene. Monitor your blood sugar regularly while taking this medicine. Inform your doctor immediately if you experience constant dizziness, joint pain, cold-like symptoms or unexplained nausea/vomiting.

History of a serious hypersensitivity reaction and hypersensitivity to canagliflozin. Severe renal impairment (eGFR <30 mL/min/1.73 m2), end stage renal disease or patients on dialysis. Diabetic Ketoacidosis, Type-1 Diabetes.

Decreased efficacy w/ rifampicin. Increase AUC & Cmax of digoxin (not clinically meaningful).

[UNSAFE] It is unsafe to consume alcohol with Canagliflozin.

[CONSULT YOUR DOCTOR] Canagliflozin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Information regarding the use of Canagliflozin during breastfeeding is not available. Please consult your doctor.

[UNSAFE] Canagliflozin is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor. [CAUTION] Canagliflozin should be used with caution in patients with severe liver disease. Dose adjustment of Canagliflozin may be needed. Please consult your doctor. Dose adjustment is not needed in patients with mild to moderate liver disease. Limited information is available on use of Canagliflozin in severe liver disease.

Type 2 diabetes for about 15 -18 years , Uncontrolled from last 2 years , present hba1c(12) , Recently consulted a DM(endocrine) and was advised few conventional medicines +Basalog(20 units)+ sulisent 100mg (1 month )+specially advised diet chart . Sugar levels are in excellent control after using it for about 4 weeks, How long can we use sulisent 100mg and other medicines in combination together? or can it be reduced if sugar levels stays balanced as normal. *(Dr. advised for Victoza , if the above mentioned combination is not effective) if sugar levels are controlled then continue samesulisent is canagliflozin which is a more or less new drug but it&#x27;s very effectivebut one thing you should take care that it can cause urinary tract infections so always beware of it Diabetes mellitus type 2 ,thirst A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET My fasting sugar level is 121 and post breakfast is 265 pl suggest medical help. Presently l am consuming sulisent 100mg It is not good control.A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET 10:07 AM 10:07 AM Ic attach file black 24 px Type your message Ic send black 24 px About Us T & C Diabetes mellitus type 2 required only ayurvedic medicine Go for allopathic medicine Care during type 2 diabetes mellitus?an manegment of life style. Hi Kindly once consult to Dietitian for proper diet chart Type || diabetes mellitus ischemic heart disease What did your tell u Any latest discoveris for type 1 mellitus Diabetes? Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes). Sex problem due to diabetes mellitus keep ur fasting sugars around 100 and take tablet dejac t 1 hr befr sex