oshudhkosh

Carbazin CR200mg

Rx
Company:
Eskayef
Dosage form:
Tablet
Pack size:
Strip (10 Tablet)

৳ 4.50/unit

Pack: ৳ 45

At a glance

Carbamazepine — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Carbamazepine is an anti-epileptic medicine used to treat epilepsy. It helps prevent certain types of seizures (fits). It is also prescribed for a painful condition of the face, head, and neck known as trigeminal neuralgia and diabetes-related nerve pain (diabetic neuropathy). Carbamazepine is also occasionally used to treat certain serious mood disorders (eg. bipolar disorder) when other medicines have not worked. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. It may be increased gradually. Many other medicines can interfere with this medicine so tell your doctor about all the medicines you are taking to make sure it is safe. You can take this medicine with or without food but take it regularly at the same time each day to get the maximum benefit. It is important to take this medicine for as long as you are advised, even if you feel well. Missing even a single dose may trigger a seizure and, if you stop taking it abruptly, your condition may get worse. The most common side effects of this medicine include nausea, vomiting, feeling dizzy, tired or drowsy, unsteadiness (balance disorder), constipation, dry mouth, and itching. Some people may develop blurring of vision and slurred speech. Most of the side effects are not serious. However, let your doctor know straight away if you notice a skin rash or if your mood becomes depressed or if you develop any thoughts about harming yourself. Before taking Carbamazepine, tell your doctor if you have any heart problems, kidney or liver disease, difficulty in urinating, epilepsy (seizure disorder or fits), or any mental illness like depression. These conditions may affect your treatment. You may be advised some blood tests (eg. CBC) before starting treatment and then periodically thereafter, to monitor your progress. Carbamazepine is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Indications

• Epilepsy/Seizures • Trigeminal neuralgia

Mechanism of action

Carbamazepine reduces polysynaptic responses and blocks post-tetanic potentiation. It is effective in partial and generalised convulsions as well as in mixed types but not in petit mal seizures. It reduces or abolishes pain in trigeminal and glossopharyngeal neuralgia.

Dosage

Adult Dose: Oral Epilepsy Adults - Initial: Either 200 mg b.i.d. for tablets and XR tablets, or 1 teaspoon q.i.d. for suspension (400 mg/day). Increase at weekly intervals by adding up to 200 mg/day using a b.i.d or a t.i.d. or q.i.d. regimen of the either formulations until the optimal response is obtained. Doses up to 1600 mg daily have been used in adults in rare instances. Maintenance: usually 800-1200 mg daily. Trigeminal neuralgia Adult: Initially, 100-200 mg bid, increased gradually as needed. Maintenance: 400-800 mg daily in divided doses. Max: 1.2 g daily. Prophylaxis of bipolar disorder Adult: Initially, 400 mg daily in divided doses, increased gradually as necessary. Maintenance: 400-600 mg daily in divided doses. Max: 1.6 g daily. Child Dose: Epilepsy 12 Years Initial (oral suspension): 10 mL (200 mg) PO q6hr Initial (tablet, immediate- or extended-release): 200 mg PO q12hr May increase by up to 200 mg/day qWeek; q12hr (extended-release tablet); q6-8hr (other formulations) 12-15 years: Dose not to exceed 1000 mg/day >15 years: Dose not to exceed 1200 mg/day

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Carbamazepine may be taken with or without food, but it is better to take it at a fixed time.

Missed dose

If you miss a dose of Carbamazepine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects

Common: • Balance disorder (loss of balance) • Dizziness • Drowsiness • Nausea • Slurred speech • Vomiting • Blurred vision • Constipation • Dryness in mouth • Fatigue • Itching

Precautions & warnings

[UNSAFE] Carbamazepine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Take your medication regularly as directed by your doctor as missing doses can trigger seizures. Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you. Some healthy tips to prevent seizures: It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you. Your doctor may get regular tests done to monitor the level of blood cells in your blood while taking this medication. Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts. Inform your doctor if you notice a rash or other skin changes such as reddish spot or circular patches while taking this medicine. Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Contraindications

Hypersensitivity; bone marrow depression; porphyria, pregnancy.

Drug interactions

Increased plasma levels w/ CYP3A4 inhibitors (e.g. cimetidine). Decreased plasma levels w/ CYP3A4 inducers (e.g. cisplatin). Increased risk of neurotoxic side effects w/ lithium. May decrease the effect of hormonal contraceptives. Increased plasma levels of active metabolite carbamazepine-10, 11-epoxide w/ loxapine, quetiapine, primidone, progabide, valproic acid and valpromide. May increase cyclophosphamide levels. May reduce exposure of aripiprazole. May reduce plasma levels of tacrolimus, temsirolimus and lapatinib. May increase risk of isoniazid-induced hepatotoxicity. Risk of symptomatic hyponatraemia w/ diuretics (e.g. hydrochlorothiazide, furosemide). Potentially Fatal: May decrease serum concentrations of nefazodone and its active metabolites. Toxic reactions may develop when taken concurrently w/ MAOIs.

Food interactions

[UNSAFE] Carbamazepine may cause excessive drowsiness with alcohol.

Use in pregnancy

[CONSULT YOUR DOCTOR] Carbamazepine is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Carbamazepine is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Renal / hepatic impairment

[CONSULT YOUR DOCTOR] There is limited information available on the use of Carbamazepine in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Carbamazepine in patients with liver disease. Please consult your doctor.

Common questions

Sir I am having ear and facial pain in the ear from past 3 years when I will journey outstation and chewing more means pain will trigger I showed to ent doctors told me that absolutely no infection I am suspecting trigeminal neuralgia plz give me some sujjestion I am taking pain killer while pain coming means pain will trigger extreme cold and hot seasons Plz send me the details Start tab tegrital 200 mg bd Do Mri brain having nerve pain in head and mouth. do mri brain; start tab tegrital 200 mg od Sir i have been taking tegrital 200 for epileptic fits for the last 21 years. I had fits when i was 24 and doctor prescribed 2 tabs of tegrital 200 daily. I started the medicine and it is working fine till date. I havent seen my doctor ever since. Is it safe to take this drug for such a long time? Usual treatment duration for epilepsy is for three years, after which medicines are gradually tapered of. Tegrital(carbamazepine) can have ill effect on kidneys. You need regular Kudney Function Test and Complete Blood Counts to monitor any side effect. Sinus, frequent cold, trigeminal neuralgia Use BADAM ROGAN TAIL - 1-1 Drop in each nostril( Nose opening ) at night Suffering from trigeminal neuralgia for 9 years, it started with one side of face that is now over all face, in past the dentist had removed a teeth to alleviate but it increased In morning the pain is at high, Tegrital(100gm)half tab worse the situation, just trika(1mg) gives some relief not sure; show to neuro Left side headache while laughing or coughing for 20 seconds only Pls suggest could be trigeminal neuralgia/ TM joint stifness or migrainerefer to ENT doctor and Neurophysician ?? ???? ?????? ?? ?????? ?? ?? ??? encorate Charon 200 500 tablet use krta hu kya iska koi solution h Jisse main completely thk ho jau Epilepsy requires regular treatment with anticonvulsants like encorate chrono for at least 3 years of seizure free period after which medicines may be tapered off unless seizures reappear. At present, there are no other effective treatment options. Trigeminal neuralgia, frequent urine, loss of mental balance record suggests encephalopathy of unclear causeneeds to be investigated

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.