Cilosta 100
Rx- Generic:
- Cilostazol
- Company:
- Square Pharmaceuticals PLC.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 12.09/unit
Pack: ৳ 120.90
At a glance
Cilostazol — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Cilostazol is used in the treatment of pain in legs due to insufficient blood flow (intermittent claudication). It also helps in reducing cramping, numbness, or weakness in the legs that occurs on walking in such patients. Cilostazol should be taken regularly as advised by the doctor. You should take it on an empty stomach and at a fixed time. This medicine should not be stopped abruptly without consulting the doctor. It may cause side effects like headache, edema, nausea, diarrhea, dizziness and chest pain. Use of this medicine may increase your risk of bleeding. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool. This medicine may not be suitable for some people. You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it. Cilostazol widens the blood vessels and decreases the stickiness of the platelets, thereby increasing the blood flow to the lower limbs.
Indications
• Intermittent claudication
Mechanism of action
Cilostazol is a reversible, selective inhibitor of phosphodiesterase-III (PDE-III), thereby suppressing cyclic adenosine monophosphate (cAMP) degradation. Increase in cAMP in platelets and blood vessels leads to inhibition of platelet aggregation and vasodilation. Cilostazol also inhibits adenosine uptake into cells, which augments the cAMP-elevating effect of PDE-III inhibition.
Dosage
Adult Dose: Oral Peripheral vascular disease Adult: 100 mg bid. May reduce dose in patients taking enzyme inhibitors concurrently. Hepatic Impairment Moderate to severe: Use caution Renal Dose: Renal Impairment CrCl< 25 mL/min: Use caution
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cilostazol is to be taken empty stomach.
Missed dose
If you miss a dose of Cilostazol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Headache • Palpitations • Abnormal stool • Diarrhea • Dizziness • Chest pain • Loss of appetite • Bleeding • Rash
Precautions & warnings
[UNSAFE] Cilostazol may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Take it at least half an hour before or two hours after breakfast and dinner. It may take up to 12 weeks before your symptoms improve. Keep using the medication as directed. Consult your doctor, if your symptoms do not improve after 4 weeks of treatment. It may cause dizziness. Don't drive or do anything that requires mental focus until you know how it affects you. Do not take it if you have heart failure, persistent chest pain at rest, or have had a heart attack or any heart surgery in the last six months.
Contraindications
Heart failure; known predisposition to bleeding; history of ventricular arrhythmias; QT interval prolongation; severe renal impairment; moderate to severe hepatic impairment.
Drug interactions
Co-admin with drugs that affect CYP3A4 (erythromycin, other macrolides, diltiazem) or CYP2C19 (omeprazole) may influence the pharmacokinetics of cilostazol.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Cilostazol. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Cilostazol may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Cilostazol is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[CAUTION] Cilostazol should be used with caution in patients with severe kidney disease. Dose adjustment of Cilostazol may be needed. Please consult your doctor. [CAUTION] Cilostazol should be used with caution in patients with liver disease. Dose adjustment of Cilostazol may be needed. Please consult your doctor. Use of Cilostazol is not recommended in patients with moderate and severe liver disease as the information available in these patients is limited.
Common questions
I am TIA patient taking ARRENO and statin (20mg) for last 3 years as clopidogrel did not suit me. Recently i developed leg pain especially after long walk and while sleeping. Colour doppler indicated Astheroclerotic wall calcification in anterior and posterior tibial arteries of lower limbs. Since i am already taking arreno, doctor did not advise me any medicine and only when pain increases over a period of time i can think of. Recently i developed little more (still i can walk without pain for 3 km a day normal walk). I got done CT angio which indicated both anterior and posterior of both legs are severely hypoplastic. The vascular specialist suggested me to take Stiloz 50mg along with Arreno. I seek advise whether i can take both these medicines that have identical in terms of mechanism of work. Will i have any problem if i take Stiloz along with Arreno ? Kindly advise. Stiloz has different action U can take it along side What is medicine for claudication Please consult a vascular surgeon There is coldness in my feet and it is causing pain especially below knees Please help me It could be claudication, so kindly consult Surgeon Can u please tell me exercises done for cervical pain Intermittent Cervical traction and Isometric cervical exercises Back pain during 8th month of pregnancy This is normal if it's not intermittent I have three months claudication in legs my calf pain from three months Mag phos 30 2 pills 4 times in day (Take Medicine for 15 days then after give me your follow up) VIGORA FORCE 50 MG/30 MG TABLET Hi kindly consult to allopathic doctor as I am an Ayurveda doctor Thyroid problem starting eltroxin 50 mcg tablet Hows thyroid level now