৳ 0.70/unit
Pack: ৳ 0.70
৳ 0.70/unit
Pack: ৳ 0.70
At a glance
Cinnarizine is an antihistamine used for the treatment of motion sickness, vertigo, and Meniere's disease.
Indications
- Motion sickness
- Vertigo
- Meniere's disease
- Cerebral vascular disorders
- Peripheral vascular disorders
- Migraine
- Tinnitus
Pharmacology
Cinnarizine acts as an antihistamine, labyrinthine sedative and a peripheral antivasoconstrictor. Cinnarizine is a selective calcium antagonist, inhibiting the influx of Ca2+ intracellularly. It prevents the Ca2+ dependent contraction of arterial smooth muscle by inhibiting Ca2+ influx through smooth muscle calcium channels and thereby, improves vestibular symptoms and prevents peripheral arterial disease.
Dosage
Adult Dose (Oral):
| Indication | Dose | Schedule |
|---|---|---|
| Peripheral vascular disease | 75 mg | 2-3 times daily |
| Motion sickness | 30 mg (2 hours before travel), then 15 mg | Every 8 hours during journey |
| Cerebrovascular disorders | 75 mg | Once daily |
| Vertigo and vestibular disorders | 30 mg or 75 mg | 3 times daily or 1-2 times daily |
Pediatric Dose (5-12 years): Half of the adult dose.
Side effects
Common Side Effects:
- Sleepiness
- Nausea
- Weight gain
- Indigestion
- Gastrointestinal disturbances
Rare Side Effects: Allergic skin reactions, fatigue, extrapyramidal symptoms (elderly in prolonged therapy).
Use in pregnancy
[CONSULT YOUR DOCTOR] Cinnarizine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Precautions & warnings
- [UNSAFE] Cinnarizine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
- Take it with food to avoid stomach upset.
- Do not drink alcohol (may cause increased sleepiness).
- Avoid driving or activities requiring mental focus until you know how it affects you.
- Stop taking if you experience yellowing of skin, tiredness, fever, nausea, weakness, red, lumpy, and itchy rash.
- Caution if suffering from Parkinson's disease (may worsen the condition).
- Do not stop taking without talking to your doctor first.
Overdose effects
Cinnarizine overdose symptoms include drowsiness, lethargy, dystonia, and extrapyramidal symptoms. Treatment is symptomatic and supportive.
Storage conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.