৳ 20/unit
Pack: ৳ 20
৳ 20/unit
Pack: ৳ 20
At a glance
Cetirizine Dihydrochloride is an antihistamine used to treat various allergic conditions such as hay fever, conjunctivitis, skin reactions, and reactions to bites and stings.
Indications
- Seasonal & Perennial Allergic Rhinitis
- Uncomplicated skin manifestations of Chronic Idiopathic Urticaria
- Allergen-induced Asthma
- Allergic Conjunctivitis
- Reactions to bites and stings
Pharmacology
Cetirizine Hydrochloride is a potent H1 receptor antagonist without any significant anticholinergic and antiserotonic effects. At pharmacologically active dose levels, it has almost no drowsiness effect and does not cause behavioral changes. It inhibits the histamine-mediated early phase of the allergic reaction and also reduces the migration of inflammatory cells and the release of mediators associated with the late phase of the allergic reaction.
Dosage
Adult Dose (Oral): 10 mg once daily or 5 mg twice daily.
Elderly: Initial: 5 mg once daily.
Hepatic Dose: Initial: 5 mg once daily.
Pediatric Dose (Oral):
| Age | Dose |
|---|---|
| 6-23 months | 2.5 mg once daily (max 2.5 mg twice daily for >12 months) |
| 2-5 years | 5 mg once daily or in 2 divided doses |
| 6 years and older | 10 mg once daily or in 2 divided doses |
Syrup Dose: Adults: 2 teaspoon once daily or 1 teaspoon twice daily; >6 years: 2 teaspoon once daily or 1 teaspoon twice daily; 2-6 years: 1 teaspoon once daily or ½ teaspoon twice daily; <2 years: Safety and efficacy not established.
Injection Dose (IV - ≥12 years): 10 mg IV injection; 6-11 years: 5-10 mg; 6 months-5 years: 2.5 mg.
Renal Dose: GFR >50 mL/min: No adjustment needed; GFR ≤50 mL/min: 5 mg once daily; Peritoneal dialysis: 5 mg once daily; Hemodialysis: 5 mg once daily or 3 times weekly.
Side effects
Common Side Effects:
- Somnolence (most common)
- Dizziness
- Dry mouth
- Fatigue
Use in pregnancy
[SAFE IF PRESCRIBED] Cetirizine Dihydrochloride is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. Pregnancy Category B. Should be used during pregnancy only if clearly needed.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- [SAFE] Cetirizine Dihydrochloride does not usually affect your ability to drive. However, exercise caution as it may cause dizziness and sleepiness.
- Stop taking Cetirizine Dihydrochloride at least three days before taking an allergy test as it can affect the test results.
- Do not drink alcohol as it may cause increased sleepiness.
- Exercise caution while driving or doing anything that requires concentration.
- Consult your doctor if you have kidney or liver problems.
Overdose effects
Cetirizine overdose symptoms include somnolence, restlessness, headache, palpitations, and urinary retention. Treatment should be symptomatic.
Storage conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.