৳ 28/unit
Pack: ৳ 28
৳ 28/unit
Pack: ৳ 28
At a glance
Betamethasone 0.05% + Clotrimazole 1% Topical is a combination medicine used to treat various types of skin infections, usually fungal infections. It minimizes symptoms of inflammation such as redness, swelling, and itching and acts against the infection-causing microorganisms.
Indications
- Inflammatory dermal infections
- Tinea pedis
- Tinea cruris
- Tinea corporis
Pharmacology
Clotrimazole is a broad-spectrum antifungal agent used for the treatment of superficial infections caused by species of pathogenic dermatophytes, yeasts and Malassezia furfur. The mechanism of action involves inhibition of the synthesis of ergosterol, a major sterol in the fungal cell membrane. This leads to instability of the cell membrane and eventual death of the fungus. Betamethasone dipropionate is a corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. But the exact mechanism of action of corticosteroids is not clearly known.
Dosage
Adults: Apply a thin layer to the affected area twice daily.
- Tinea corporis and tinea cruris: Up to 2 weeks
- Tinea pedis: Up to 4 weeks
- Maximum weekly dose: 45 g
Children (under 17 years): Safety and efficacy have not been established.
Side effects
- Application site burning, itching, redness
- Thinning of skin
- Skin peeling
- Paresthesia (1.9%)
- Dry skin (1.6%)
- Stinging (<1%)
- Rash, edema, secondary infection (<1%)
Use in pregnancy
[CONSULT YOUR DOCTOR] There is inadequate evidence of safety in pregnancy. Clotrimazole has no teratogenic effect in animals but is foetotoxic at high oral doses. Topical corticosteroids can cause fetal abnormalities in animals. Use only if the benefit justifies the potential risk and not for large areas or long periods.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- For use on skin only; avoid eyes, mouth, and vagina
- Do not use occlusive dressings unless directed by a doctor
- If severe irritation or allergy occurs, discontinue use
- Do not use for longer than 4 weeks without medical advice
- Inform your doctor if no improvement after 2 weeks
- Caution during pregnancy and lactation
Overdose effects
Acute overdose is unlikely and not life-threatening. Do not use for longer than prescribed.
Storage conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.