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Hydrochlorothiazide + Valsartan is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure. You can take Hydrochlorothiazide + Valsartan with or without food. The dose will depend on your condition and how your respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase. The most common side effect is dizziness. Other side effects include feeling tired, nausea, diarrhoea, headache and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of hydrochlorothiazide and helps control your blood pressure. You may experience other possible side effects, but most are rare. Hydrochlorothiazide may occasionally lead to an increase in pressure in your eye and lead to permanent eye damage if not treated. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine. Do not use potassium supplements or salt substitutes unless your doctor has told you to. This medicine is not recommended during pregnancy or while breastfeeding and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects. Hydrochlorothiazide + Valsartan is a combination of two medicines: Valsartan and hydrochlorothiazide which lower blood pressure effectively. Valsartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

• Hypertension (high blood pressure)

Valsartan is an angiotensin II receptor antagonist and reduces blood pressure by blocking the vasoconstrictive and aldosterone-secreting effects of angiotensin II. Hydrochlorothiazide is a thiazide diuretic.

Adult Dose: Hypertension 1 tablet/day PO (80-160 mg valsartan/12.5-25 mg hydrochlorothiazide); may be titrated after 1-2 weeks of therapy; not to exceed 320 mg valsartan/25 mg hydrochlorothiazide daily Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Not recommended.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hydrochlorothiazide + Valsartan may be taken with or without food, but it is better to take it at a fixed time.

Common: • Nausea • Taste change • Diarrhea • Upset stomach • Dizziness • Decreased blood pressure • Headache • Fatigue • Increased blood lipid level • Electrolyte imbalance • Increased blood uric acid • Glucose intolerance

[UNSAFE] Hydrochlorothiazide + Valsartan may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Hydrochlorothiazide + Valsartan for the treatment of high blood pressure. It can be taken with or without food. Hydrochlorothiazide + Valsartan may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness. It may cause dizziness. Get up slowly when rising from a sitting or lying position. Use of Hydrochlorothiazide + Valsartan during pregnancy or breastfeeding is unsafe. It may also decrease the risk of stroke and heart attacks.

Hypersensitivity to valsartan, hydrochlorothiazide or sulphonamides. Severe hepatic impairment, creatinine clearance <30ml/min, anuria, cirrhosis, biliary obstruction, conditions where there is increased potassium loss (e.g. salt losing nephropathies and pre-renal impairment of kidney function), refractory hypokalaemia, hyponatraemia, hypercalcaemia, hyperuricaemia, history of gout and uric acid stones, untreated Addison's disease. Pregnancy and lactation.

Increased antihypertensive effect with other antihypertensive drugs. Monitor potassium frequently if used with potassium supplements, potassium-sparing diuretics, salt substitutes containing potassium, or drugs that may affect potassium levels (e.g. heparin, ciclosporin, drospirenone, amphotericin, corticosteroids, carbenoxolone). Reduced antihypertensive effect of valsartan and increased risk of renal impairment with NSAIDs. May reduce renal clearance of cytotoxic drugs (e.g. cyclophosphamide, methotrexate). Increased serum calcium with vitamin D or calcium salts. Potentially Fatal: Increased lithium levels with valsartan, monitor lithium levels. Increased risk of cardiac arrhythmia with dofetilide, avoid use.

[UNSAFE] It is unsafe to consume alcohol with Hydrochlorothiazide + Valsartan.

[CONSULT YOUR DOCTOR] Hydrochlorothiazide + Valsartan is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[SAFE IF PRESCRIBED] Hydrochlorothiazide + Valsartan is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Hydrochlorothiazide + Valsartan should be used with caution in patients with severe kidney disease. Dose adjustment of Hydrochlorothiazide + Valsartan may be needed. Please consult your doctor. Use of Hydrochlorothiazide + Valsartan is not recommended in patients with severe kidney disease. [CAUTION] Hydrochlorothiazide + Valsartan should be used with caution in patients with liver disease. Dose adjustment of Hydrochlorothiazide + Valsartan may be needed. Please consult your doctor.

I have 110-170 blood pressure,sugar fasting100,cholostrol normal ,but now l have very high headache with pain only one side(left) whatever medicine u taking for BP stop that and take ramistar H once daily High blood pressure around 201/119 headache and stomach pain Dr can u help urgently I have given her telma h Telma H will not helpTake her to a hospitalPatient has to be monitoredTab Dipin 5mg 2 times a dayTake only if hospital unavailable Systolic Blood pressure 145mm h Repeat bp after 48 hrs & inform Suffering from High Blood Pressure. Want to know alternative drug for Olmesmart H. y do u want to change Diarrhea, stomach pressure leading to loose motions Tab Domstal 1 SOS, Tab O2 H 1 BD x. 3 days. ORS I have stomach problem i am take the food nd after 1 hr taking the food crate the pressure in my stomach i have goto the flash. Tab O2 H 1 bd x 3 days Ankle (leg) edima/odema Patient have diabetics. B.P Patient is on insulin&#x27;s two time, one tab of B.P (valent h) At night aspirin tab, Sugar is normal Last 10 days edima on ankle leg use mehanil tab , rajniamalak churna , gudmar and gokshura churna I am a patient of hypertension Hypertension is clinal condition of high blood pressure. Please see a physician.