Comtan 200 mg200mg

• Parkinson's Disease: Used in combination with levodopa for the treatment of Parkinson's disease, particularly for "end-of-dose" motor fluctuations.

Adult Dose:

• Parkinson's Disease (with levodopa): 200 mg with each levodopa/dopa decarboxylase inhibitor dose. Max: 200 mg 10 times daily (2,000 mg daily).
• Hepatic Impairment: Safety and efficacy not established.

Renal Dose: No dose adjustment necessary in renal impairment.

Common Side Effects:

• Nausea
• Vomiting
• Fatigue
• Confusion
• Constipation
• Insomnia (difficulty in sleeping)
• Nightmares
• Hallucination
• Increased sweating
• Fall
• Urine discoloration
• Dizziness
• Diarrhea
• Muscle coordination impaired
• Ischemic heart disease
• Heart attack
• Abdominal pain
• Dryness in mouth

Precautions:

• Entacapone may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.
• It can make you very sleepy. Don't drive or do anything requiring concentration until you know how it affects you.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
• Inform your doctor if you develop impulsive, unusual behavior and/or an abnormally high sex drive.
• Talk to your doctor in case you develop hallucinations or other changes in your behavior.
• It is common to have diarrhea with this drug. Therefore, drink plenty of fluids and watch for weight loss.
• Do not get worried if you notice a reddish-brown discoloration in your urine as it is harmless in nature.
• Do not stop taking the medication suddenly without talking to your doctor.