Conpan 2
Rx- Generic:
- Clonazepam
- Company:
- Navana Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 11.50/unit
Pack: ৳ 115
At a glance
Clonazepam — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Clonazepam is a prescription medicine used to treat epilepsy (seizures), panic and anxiety disorder. It helps to decrease the abnormal and excessive activity of the nerve cells and calms the brain. Clonazepam may be taken with or without food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. You should not stop this medicine suddenly without talking to your doctor as it may increase the seizure frequency and can cause nausea, anxiety, flu-like symptoms, and muscle pain. Some common side effects of this medicine include fatigue, depression and impaired coordination. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts. Clonazepam is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.
Indications
• Anxiety disorder • Epilepsy/Seizures
Mechanism of action
Clonazepam reduces the nerve transmission in the motor cortex which suppresses the spike and wave discharge in absence seizures. Its mechanism is believed to be related to its ability to enhance the activity of GABA. Clinically, it improves focal epilepsy and generalised seizures.
Dosage
Adult Dose: Oral Epilepsy Adult: Initially, 1 mg given at night for 4 days, gradually increased over 2-4 wk. Maintenance: 4-8 mg/day. Max: 20 mg/day. Elderly: Initially, 0.5 mg at night for 4 days. Panic disorder Adult: Initially, 0.25 mg bid, increased after 3 days up to 1 mg/day. Max: 4 mg/day. Intravenous Emergency management of status epilepticus Adult: 1 mg by slow IV inj over at least 2 min or by infusion, repeated if necessary. Max: 20 mg. Hepatic impairment: Dosage adjustment may be needed. Child Dose: Oral Epilepsy Child: <10 yr or <30 kg: Initially, 0.01-0.03 mg/kg/day but not to exceed 0.05 mg/kg/day given in 2 or 3 divided doses. May be increased by no more than 0.25-0.5 mg every 3rd day until seizure control is achieved. Maintenance: 0.1-0.2 mg/kg/day divided 3 times daily. Max: 0.2 mg/kg/day. Intravenous Emergency management of status epilepticus Child: 500 mcg by slow IV inj or by infusion.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clonazepam may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Clonazepam, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Depression • Dizziness • Drowsiness • Fatigue • Impaired coordination
Precautions & warnings
[UNSAFE] Clonazepam may cause side effects which could affect your ability to drive. The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid consuming alcohol as it may increase dizziness and drowsiness. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. Inform your doctor if you experience worsen anxiety, depression angry, or violent behavior and mania while taking this medicine. Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
Contraindications
Hypersensitivity to benzodiazepines, acute pulmonary insufficiency, acute narrow angle glaucoma.
Drug interactions
Additive depressant effect w/ TCAs, MAOIs, sedative and hypnotics, barbiturates, anxiolytics, antipsychotics, opiate agonists. May increase serum phenytoin levels.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Clonazepam.
Use in pregnancy
[CONSULT YOUR DOCTOR] Clonazepam is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Clonazepam is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Renal / hepatic impairment
[CAUTION] Clonazepam should be used with caution in patients with kidney disease. Dose adjustment of Clonazepam may be needed. Please consult your doctor. Use of Clonazepam can cause excessive sleepiness in patients with end stage kidney disease. [CAUTION] Clonazepam should be used with caution in patients with liver disease. Dose adjustment of Clonazepam may be needed. Please consult your doctor.
Common questions
My Sister(pott's spine patient) underwent spine decompression surgery recently where she got got 2 rods and screws fixed to her backbone to support the spine. She started walking slowly the next day and seemed to do pretty well. However with some time, she complains of getting sudden jerks in her back while walking and can't bear the pain. DOTS IV is still being administered. The Neuro surgeon says you are being lazy and not walking enough and doesnt give much time or importance to our problem statement. I cannot understand what could be the problem and what can be the solution. Please guide. I am yet to take her to LRSI hospital for TB treatment progress monitoring. start tab lonazep 0.25 mg at nite; show to neurologist 24 hours vertigo attacks and palpitation at the same time please give any reply Start tab lonazep 0.25 mg bdFor a week Get examined Lonazep md 0.25 is not available what to do Try plain lonazep or use another brand Can I take Feliz s 10 & Lonazep .25 mg at night for anxiety disorder & lack of sleep Psychiatric evaluation is based on history, clinical symptoms, personality factors, ongoing psychosocial stressors and frequency and severity of symptoms. It requires direct interaction with the patient on a regular basis. Once diagnosed, a management plan is formed based on intensity and frequency of symptoms and associated biological and psycho social factors. A complete solution to ones problems in a single question is thus not possible. I suggest you to visit a psychiatrist in your vicinity for clinical evaluation. I have sleep disorder from last 8 years. During the sleep dreams comes. I took quatan 25mg and nexito forte approx 5 years.After changing the doctor i have been prescribed mirtaz 7.5mg ,nexito 10 and 0.5 lonazep fir 2 years. After that i took sertraline 50mg ,lonazep 0.5mg then 100 mg sertraline ,lonazep 0.5mg then mirnite 15mg then 100 mg sertraline ,lonazep 0.5mg and arip mt-5 . I am getting a solutions for sleep disorder. You are requested to review and advise me. Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Please go through the link below - http://drjyotikapoor.com/2015/01/26/sleep-disorders/ Is there any side effect of continuous taking cipralex 10 mg. Lonazep .25 mg. & Etilaam .25 mg. one each daily for 4 to 5 months for treatment of anxiety. Whether one can get addiction to any one of these & are they quiet safe? Please tell whether a person can be fully recovered from depression with the help of aforesaid medicines with long usage? Antidepressants are not addictive. Lonazep and etilaam are benzodiazepines which can be addictive if not taken under supervision. mental depression. I use nexito20,mirtaz15 lonazep.25 Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.