Criston 1
Rx- Generic:
- Vincristine Sulphate
- Company:
- Beacon Pharmaceuticals PLC
- Dosage form:
- Injection
- Pack size:
- Injection
Save to my medicines
Alert me on price drop
৳ 1/unit
Pack: ৳ 1
At a glance
Vincristine Sulphate is an anti-cancer medication used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cancer, multiple myeloma, lymphomas and bone cancer.
Indications
- Breast cancer
- Non-small cell lung cancer
- Pancreatic cancer
- Kidney cancer
- Blood cancer
- Multiple myeloma
- Lymphomas
- Bone cancer
- Acute leukemia
- Hodgkin's disease
- Non-Hodgkin's malignant lymphomas
- Rhabdomyosarcoma
- Neuroblastoma
- Wilms' tumor
Dosage
Adult Dose (IV):
- Acute lymphoblastic leukaemia: 1.4-1.5 mg/m² once weekly; max 2 mg weekly
- Hepatic impairment: If serum bilirubin >3 mg/100ml, reduce dose by 50%
Child Dose (IV):
- Acute lymphoblastic leukaemia: 1.5-2 mg/m² once weekly; for patients ≤10 kg: initiate at 0.05 mg/kg once weekly
Renal Impairment: Dose adjustment not necessary
Side effects
Common Side Effects:
- Hair loss
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Constipation
- Nausea
- Vomiting
- Diarrhea
- Decreased appetite
- Decreased white blood cell count
- Stomatitis
- Neurotoxicity
Precautions & warnings
- May affect ability to drive
- Avoid being near people suffering from infections; leukopenia possible
- Avoid even accidental contamination of eyes
- May cause acute kidney disease related to uric acid level
- Elderly are more susceptible to neurotoxic effects
- May cause aspermia (infertility) in males; amenorrhea in females
- Consult doctor if pregnant or breastfeeding
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.