Danzol 100

• Endometriosis
• Benign breast disease (fibrocystic breast disease)
• Menorrhagia
• Gynecomastia
• Hereditary angioedema
• Preoperative thinning of the endometrium before hysteroscopic endometrial ablation

Adult - Endometriosis: 200-800 mg daily in 2-4 divided doses, adjusted to achieve amenorrhoea, usually for 6 months (up to 9 months in some cases).

Adult - Menorrhagia: 100-200 mg daily, 200 mg daily for 3 months is usually sufficient.

Adult - Benign breast disease: 100-400 mg daily in 2 divided doses for 3-6 months.

Adult - Gynecomastia: 400 mg daily in up to 4 divided doses for 6 months (adolescents: 200 mg daily, increased to 400 mg if no response after 2 months).

Adult - Hereditary angioedema: Initially 200 mg 2-3 times daily, reduced thereafter according to response.

Adult - Preoperative endometrial thinning: 400-800 mg daily for 3-6 weeks.

Common Side Effects:

• Hoarseness of voice
• Hair loss
• Weight gain
• Acne
• Abnormal hair growth on face and body (women)
• Voice change
• Itchy scalp
• Swelling
• Sore throat
• Menstrual irregularities
• Vaginal dryness and irritation
• Flushing
• Reduction in breast size

Serious Side Effects:

• Virilization (voice changes, hirsutism, clitoral hypertrophy)
• Benign intracranial hypertension (headache, visual disturbances)
• Thromboembolic events
• Leukopenia, thrombocytopenia
• Insulin resistance
• Liver function changes

• May affect your ability to drive (dizziness, spinning feeling, changes in eyesight).
• If signs of virilization occur (voice changes or hirsutism), therapy should be stopped immediately.
• Caution in cardiac, hepatic or renal impairment, diabetes, hypertension, migraine, history of thrombosis.
• Use non-hormonal contraceptive methods to avoid pregnancy.
• Regular monitoring of liver function tests is advised.