Defera 500

Deferiprone is a medicine used in the treatment of chronic iron overload caused due to frequent blood transfusion. It helps removes excess iron and reduces the risk of it causing organ damage. Deferiprone should be taken in empty stomach. Take it regularly at a fixed time each day to get the maximum benefit of the medicine. Using of Deferiprone may cause common side effects such as nausea, headache, constipation, diarrhea and increased liver enzyme. If the side effects persist or worsen, inform your doctor. Deferiprone traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.

• Iron overload • Transfusion dependent thalassemia

Deferiprone is an orally effective iron-chelating agent. It is being used when desferrioxamine is unsuitable or contraindicated.

Adult Dose: Transfusional Iron Overload Iron chelator indicated for treatment of transfusional iron overload caused by thalassemia syndromes when current chelation therapy is inadequate 25-33 mg/kg PO TID (ie, total daily dosage range 75-99 mg/kg/day) Round dose to nearest 250 mg

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Deferiprone may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Deferiprone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Fatigue • Headache • Nausea • Vomiting • Abdominal pain • Joint pain • Diarrhea

[CONSULT YOUR DOCTOR] It is not known whether Deferiprone alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Seek immediate medical attention if you see symptoms of fever, sore throat, or flu as deferiprone can cause neutropenia (a decrease in white blood cells) or agranulocytosis (abnormal decrease in white blood cell count). Take precautions as deferiprone can lower the ability of your body to fight infections. Your blood will need to be tested weekly while you are taking this medication. Deferiprone may result in urine that is reddish-brown in color. This side effect is normal and usually not harmful. Take medical advice if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes). Tell your doctor if you suffer from dizziness, palpitations, light-headedness, syncope, or seizures after taking deferiprone.

Agranulocytosis, pregnancy and lactation.

Avoid using deferiprone with aluminium-containing antacids as it can chelates trivalent metal ions.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Deferiprone. Please consult your doctor.

[CONSULT YOUR DOCTOR] Deferiprone is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[CONSULT YOUR DOCTOR] Deferiprone is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Deferiprone in patients with kidney disease. Please consult your doctor. Regular monitoring of kidney function tests is advised in these patients while taking this medicine. [CONSULT YOUR DOCTOR] There is limited information available on the use of Deferiprone in patients with liver disease. Please consult your doctor. Regular monitoring of liver function tests is advised in patients with liver disease while taking this medicine.

Hello doctor I have thallassemia major since birth and due to iron overload of repetitive blood transfusion i have diagnosed with diabetes 3 yr ago -at the time of diabetes diagnosis my sugar level is 650 mg/dl. Now according to my case what could be the state of my diabetes type 1 or type 2 ? Hello, Diabetes in thalassaemia is thought to be caused mainly by iron overload, from repeated blood transfusions, damaging the pancreas. Insulin secretion may be reduced, possibly because iron is directly toxic to the insulin producing pancreatic ?-cells. So it is type 1 DM . Diabatic for last 4 years insulin dependent D Vitamin iron deficiency Dear Sir Thank you for sharing your reports with me. It shows the following important things: 1. your iron level is low, for this you can have a diet rich in lots of iron like jaggery, spinach, leafy vegetables etc. Your vitamin D level is low, for this you can have calcirol sachet in milk once a week for at least 6 weeks. Your glycosylated hemoglobin and average blood glucose level is high, you should consult your doctor for this for the review of treatment. Diabatic for last 5 years insulin dependent D Vitamin iron deficiency Hi you need to consult doctor nearby by.Or u can visit our clinic at sector 52 gurgaon in RDCITY snergy clinic. Diabetic pt should be in regular contact with the diabetologist or treating doctor. Do all regular tests and follow diet and exercise. Disease can be well controlled. A person can avoid diabetic complications. Diabatic for last 4 years insulin dependent D Vitamin n iron deficiency Take D suppliments and follow ur doctor advise What test do I ask for testing my iron content in blood plus what test will show if my daughter is thalassemia minor? CBC, Iron Studies and Abnormal Haemoglobin Studies Sir, I'm pregnant 4 month up, best vitamin capsule name please advise me. No vitamin take iron and calcium H.B is just 7 gram not improving iron not suitable Please consult Dr. will take detail history and will examine your child in detail. may ask you for blood test. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.Just to give you idea i am giving examples of diseases where anemia is presentCongenital dyserythropoietic anemia Diamond-Blackfan anemia G-6-PD deficiency Hemophagocytic lymphohistiocytosis (HLH), congenital or acquired Iron refractory iron deficiency anemia (IRIDA) Nutritional iron deficiency Paroxysmal nocturnal hemoglobinuria Pure red cell aplasia Rheumatoid arthritis Sideroblastic anemia Unstable hemoglobinopathies Hookworm infection Hypothyroidism Myelodysplastic syndrome Myelofibrosis Systemic lupus erythematosus Thalassemia Thalassemia intermedia Pyruvate kinase deficiency Hello doctor i have thallasemia major since birth and due to iron overload of repetitive blood transfusions from this disease i was diagnosed with diabetes 2 yrs. ago Now my query is can i control my sugar by controlling iron/ferritin? No you have to take insulin or Oral hypoglycemic agents for it