oshudhkosh

Depotin60mg

Rx
Generic:
Dapoxetine
Dosage form:
Tablet
Pack size:
Tablet

৳ 10/unit

Pack: ৳ 10

At a glance

Dapoxetine — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Dapoxetine is a medicine used to treat premature ejaculation in adult men. This medicine increases the time it takes to ejaculate and improve control over ejaculation. This helps to relieve the anxiety or frustration about fast ejaculation. Dapoxetine belongs to a group of medicines known as selective serotonin reuptake inhibitors (SSRI). It may be taken with or without food. This medicine should only be taken if you have been diagnosed with premature ejaculation by a doctor. It is usually advised to be taken 1 to 3 hours before anticipated sexual activity. Do not take it more than once in a day. Follow your doctor's instructions while taking this medicine. Some common side effects of this medicine include headache, dizziness, drowsiness, vomiting, nausea, indigestion, fatigue, increased sweating, and restlessness. Some people can develop erectile dysfunction with this medicine. Let your doctor know if any of the side effects persist or worry you. Do not drive or do anything that requires focus (eg. working with heavy machinery) until you know how this medicine affects you, as some people can develop dizziness and sleepiness as side effects. Do not take Dapoxetine if you have heart problems (like heart failure or problems with the heart rhythm), or have ever had depression or mania, or are currently taking medicines for depression known as MAO inhibitors. Before taking it, you should tell your doctor if you have epilepsy (seizure disorder or fits), liver or kidney disease, glaucoma, or have had dizziness/fainting (syncope) due to low blood pressure in the past. These may affect your treatment. Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) which increases the level of serotonin in the nervous system to increase the time taken to ejaculate and improve control over ejaculation.

Indications

• Premature ejaculation

Mechanism of action

Dapoxetine selectively inhibits the reuptake of serotonin. It has limited direct action at other neurotransmitter sites including muscarinic receptors.

Dosage

Adult Dose: Oral Premature Ejaculation Adult: 18-64 yr Initially, 30 mg approx 1-3 hr before sexual activity, subsequent doses adjusted according to response. Max: 60 mg. Dose should not be taken more than once in 24 hr. Review treatment after 4 wk (6 doses) and at least 6 mthly thereafter. Hepatic Impairment: Moderate to severe: Contraindicated. Renal Dose: Patients with Renal Impairment: No dose adjustment is required but caution is advised in patients with mild or moderate renal impairment. Dapoxetine is not recommended for use in the patients with severe renal impairment.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dapoxetine may be taken with or without food, but it is better to take it at a fixed time.

Missed dose

If you miss a dose of Dapoxetine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects

Common: • Drowsiness • Nausea • Tremor • Vomiting • Dizziness • Erectile dysfunction • Fatigue • Headache • Increased sweating • Indigestion • Restlessness

Precautions & warnings

[UNSAFE] Dapoxetine may cause side effects which could affect your ability to drive. You may feel sleepy, dizzy, faint, have difficulty concentrating and blurred vision while taking this medicine. This may affect your driving ability. Dapoxetine should only be taken 1 to 3 hours before sexual activity is anticipated. Do not take this medicine more than once 24 hours or every day. Do not drive or do anything requiring concentration until you know how Dapoxetine affects you. It should be used with caution in patients with history of seizures, depression and other psychiatric disorders. Dapoxetine may cause a sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down. Talk to your doctor before taking this medicine if you are suffering from erectile dysfunction.

Contraindications

Known hypersensitivity to dapoxetine HCl or to any of the excipients. Patients with significant pathological cardiac conditions [eg, heart failure (NYHA class II-IV), conduction abnormalities (2nd- or 3rd-degree AV block or sick sinus syndrome) not treated with a permanent pacemaker, significant ischemic heart disease or significant valvular disease]. Concomitant treatment with monoamine oxidase inhibitors (MAOIs), or within 14 days of discontinuing treatment with a MAOI. Similarly, a MAOI should not be administered within 7 days after Dapoxetine has been discontinued. Concomitant treatment with thioridazine, or within 14 days of discontinuing treatment with thioridazine. Similarly, thioridazine should not be administered within 7 days after Dapoxetine has been discontinued. Concomitant treatment with serotonin re-uptake inhibitors [selective serotonin re-uptake inhibitors (SSRIs), serotonin-norepinephrine re-uptake inhibitors (SNRIs), tricyclic antidepressants (TCAs)] or other medicinal/herbal products with serotonergic effects or within 14 days of discontinuing treatment with these medicinal/herbal products. Similarly these medicinal/herbal products should not be administered within 7 days after Dapoxetine has been discontinued.

Drug interactions

Potential serious reactions w/ MAOIs. Inhibits metabolism of thioridazine. Risk of serotonergic-associated effects w/ serotonergic medicinal/herbal products (including L-tryptophan, triptans, tramadol, linezolid, SSRIs, SNRIs, lithium & St. John's wort prep). CNS-active medicinal products. Possible reduction of clearance w/ CYP2D6, CYP3A4 & flavin monooxygenase 1 inhibitors. Increased exposure w/ potent (eg ketoconazole, itraconazole, ritonavir, saquinavir, telithromycin, nefazodone, nelfinavir & atazanavir) & moderate (eg erythromycin, clarithromycin, fluconazole, amprenavir, fosamprenavir, aprepitant, verapamil, diltiazem) CYP3A4 inhibitors; potent CYP2D6 inhibitors. Possible reduced orthostatic tolerance w/ PDE-5 inhibitors & ?-adrenergic receptor antagonists. Increases plasma conc of desipramine & other drugs metabolized by CYP2D6. Decreases AUCinf of midazolam. Warfarin (chronic therapy). Alcohol.

Food interactions

[UNSAFE] It is unsafe to consume alcohol with Dapoxetine.

Use in pregnancy

[CONSULT YOUR DOCTOR] Information regarding the use of Dapoxetine during pregnancy is not available. Please consult your doctor.

Use in lactation

[CONSULT YOUR DOCTOR] Information regarding the use of Dapoxetine during breastfeeding is not available. Please consult your doctor.

Renal / hepatic impairment

[CAUTION] Dapoxetine should be used with caution in patients with kidney disease. Dose adjustment of Dapoxetine may be needed. Please consult your doctor. Use of Dapoxetine is not advised in patients with severe kidney disease. [CAUTION] Dapoxetine should be used with caution in patients with liver disease. Dose adjustment of Dapoxetine may be needed. Please consult your doctor. Use of Dapoxetine is not recommended in patients with moderate to severe liver disease.

Common questions

Is it safe to take duralast for premature ejaculation? how to use duralast 30mg for premature ejaculation 1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effects Hii sir my doctor suggested me to buy duralast for premature ejaculation problem Hello PATIENT is good medicine Sir, I am suffering from premature ejaculation. and you are suggested dapoxetine 30 mg. I purchased duralast tab with dapoxetine. can I use that? kindly suggest. hi PATIENT a gym. do heavy workouts and not cardio. eat protein as in eggs and lots of veggies and fresh fruits like pomegranates. this will naturally increases ur testosterone production apart from it:1. medical treatment: Tablet tadapox or dejac-T 1 tablet 1 hour before sex 2. sex therapy: when u think u r about to come, just stop moving and ask ur partner to stop moving as well and stay still for 30 seconds. In 70%, these technique works. Other technique is to ask the partner to squeeze the glans penis with thumb and finger tightly just when u think u r about to come. This will prevent u from ejaculating. Can I take duralast 30 as half tablet being diabitic. Earlier took suhagra force 50 caused severe headache. Or can I take one tablet pl reply You can take. Drink plenty of water. Can i take as diabetic patient duralast 30 as half tablet instead full. Earlier taken suhagra force but caused severe headache. Pl reply Pls consult urologist for erectile dysfunction Premature ejeculation is my problem from last 10 years consult with Doctors from medanata. They suggested tab duralast & modula for one month. Can I continue that Hello PATIENT you feel good with those medicine then continue but I advice a bit diffrently. Premature Ejaculation is very common in age and first of all dont take so much tension which is further deteriorate your health. Life style modification with behavioural changes may help you more. There are some technique and take help from your partner. In the ?stop-start? programme, the partner stimulates the penis until the patient feels the urge to ejaculate. At this point, he instructs his partner to stop, waits for the sensation to pass and then stimulation is resumed. Another the ?squeeze? technique is similar but the partner applies manual pressure to the glans just before ejaculation until the patient loses his urge. Apply some cream like Climax spray / EMLA cream which will further help. Along with this do exercise, stop smoking tobacco alcohol n gutkha, eat fruits and take antioxidant multivitamins and vitamin C. Try this for couple of weeks and if not improved i will advice you some medicines. hello sir/madam i have sexual weakness problems in my health ( erectile dysfunction ) (premature ejecultion ) ( night fall ) so one of my friend suggest me to take duralast 30 mg tab for 30 day is ther any side effect for my kidny or other my health ??? please reply me nightfall is 100% normal so is masturbationfor ED AND PME, 1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effects Premature ejaculation less 30 sec. Premature ejaculation it is mostly psychological first u try to divert ur self in between while having sex If u r there to cum then sqeeze ur glans in between ur thumb and index finger u can also use local anaethetic jelly but then its better to use condom with that finally there are a few medicines available which will increase ur timing Consult andrologist nearby for prescription.

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.