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At a glance

Dexamethasone Sodium Phosphate is a steroid used for the treatment of severe allergic reactions, asthma, rheumatic disorders, skin disorders, eye disorders, and nephrotic syndrome.

Indications
  • Allergic conditions
  • Severe allergic reactions
  • Asthma
  • Cancer
  • Rheumatic disorders
  • Skin disorders
  • Eye disorders
  • Nephrotic syndrome
Pharmacology

Dexamethasone is a synthetic glucocorticoid which decreases inflammation by inhibiting the migration of leukocytes and reversal of increased capillary permeability. It suppresses normal immune response.

Dosage

Adult: 0.5-20 mg/day IV/IM as single dose or IV infusion; Cerebral edema: 10 mg IV, then 4 mg IM every 6 hours; Shock: 1-6 mg/kg IV once or 40 mg IV every 2-6 hours.
Child: 0.5-2 mg/kg/day IV/IM every 6 hours; Croup: 0.6 mg/kg IV/IM once; Meningitis: 0.6 mg/kg/day IV every 6 hours.

Side effects

Common: Injection site reactions (pain, swelling, redness), mood changes.
Other: Cushing syndrome, weight gain, hypertension, diabetes, osteoporosis, immunosuppression.

Use in pregnancy

Pregnancy Category C. Dexamethasone may be unsafe during pregnancy. Animal studies have shown harmful effects on the developing baby.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Does not usually affect driving ability. Increased infection risk; inform doctor if signs of infection occur. Do not stop abruptly (gradual tapering required). Caution in diabetes, hypertension, osteoporosis, peptic ulcer, glaucoma, liver and kidney disease.

Overdose effects

Treatment of overdose is by supportive and symptomatic therapy.

Storage conditions

Store as per manufacturer's instructions.

Dexamethasone Sodium Phosphate — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.